Timing-dependent LTP (t-LTP) is a physiologically relevant type of synaptic plasticity that
results from repeated sequential firing of action potentials (APs) in pre-and postsynaptic …

Glial-cell-line-derived neurotrophic factor (GDNF) is a distant member of the transforming
growth factor-β family and has potent neurotrophic effects on several classes of neurons …

The neurotrophin gene family includes four structurally related proteins with neurotrophic
activities. Two of them, nerve growth factor and brain‐derived neurotrophic factor (BDNF) …

K-252 compounds, which share a common polyaromatic aglycon structure, are rather
general and potent inhibitors of various protein kinases, including protein kinase C and …

Brain-derived neurotrophic factor is selectively expressed at relatively high levels in the rat
hippocampal formation (for review, see Ref. 12; see also Refs 8, 13, 19, 20, 27) where it is …

Development and survival of neurons in the central nervous system are dependent on the
activity of a variety of endogenous neurotrophic agents. Using combined isotopic and …

Brain derived neurotrophic factor (BDNF) is widely distributed in the central nervous system
(CNS) and has survival-promoting actions on a variety of CNS neurons. We have examined …

Motor learning depends on synaptic plasticity between corticostriatal projections and striatal
medium spiny neurons. Retrograde tracing from the dorsolateral striatum reveals that both …

Neurotrophins and their receptors are widespread in the developing and mature CNS.
Identifying the differentiation state of neurotrophin-responsive cells provides a basis for …

Chemotherapy-related cognitive deficits are a major neurological problem, but the
underlying mechanisms are unclear. The death of neural stem/precursor cell (NSC) by …