Antimicrobial peptides as therapeutic agents: Opportunities and challenges
M Mahlapuu, C Björn, J Ekblom - Critical reviews in biotechnology, 2020 - Taylor & Francis
The rapid development of microbial resistance to conventional antibiotics has accelerated
efforts to find anti-infectives with a novel mode-of-action, which are less prone to bacterial …
efforts to find anti-infectives with a novel mode-of-action, which are less prone to bacterial …
[HTML][HTML] Focus: antimicrobial resistance: antimicrobial peptides therapy: an emerging alternative for treating drug-resistant bacteria
Microbial resistance to antibiotics is an ancient and dynamic issue that has brought a
situation reminiscent of the pre-antibiotic era to the limelight. Currently, antibiotic resistance …
situation reminiscent of the pre-antibiotic era to the limelight. Currently, antibiotic resistance …
Designing antimicrobial peptides using deep learning and molecular dynamic simulations
Q Cao, C Ge, X Wang, PJ Harvey… - Briefings in …, 2023 - academic.oup.com
With the emergence of multidrug-resistant bacteria, antimicrobial peptides (AMPs) offer
promising options for replacing traditional antibiotics to treat bacterial infections, but …
promising options for replacing traditional antibiotics to treat bacterial infections, but …
[HTML][HTML] Therapeutic potential of antimicrobial peptides in polymicrobial biofilm-associated infections
G Batoni, G Maisetta, S Esin - International Journal of Molecular Sciences, 2021 - mdpi.com
It is widely recognized that many chronic infections of the human body have a polymicrobial
etiology. These include diabetic foot ulcer infections, lung infections in cystic fibrosis …
etiology. These include diabetic foot ulcer infections, lung infections in cystic fibrosis …
[HTML][HTML] Attacins: A promising class of insect antimicrobial peptides
Insects produce a large repertoire of antimicrobial peptides (AMPs) as the first line of
defense against bacteria, viruses, fungi or parasites. These peptides are produced from a …
defense against bacteria, viruses, fungi or parasites. These peptides are produced from a …
The revitalization of antimicrobial peptides in the resistance era
Y Liu, J Shi, Z Tong, Y Jia, B Yang, Z Wang - Pharmacological Research, 2021 - Elsevier
The antibiotic resistance crisis is becoming incredibly thorny due to the indiscriminate
employment of antibiotics in agriculture and aquaculture, such as growth promoters, and the …
employment of antibiotics in agriculture and aquaculture, such as growth promoters, and the …
[HTML][HTML] Recent applications of retro-inverso peptides
Natural and de novo designed peptides are gaining an ever-growing interest as drugs
against several diseases. Their use is however limited by the intrinsic low bioavailability and …
against several diseases. Their use is however limited by the intrinsic low bioavailability and …
Broad-spectrum hybrid antimicrobial peptides derived from PMAP-23 with potential LPS binding ability
Y Lyu, M Tan, M Xue, W Hou, C Yang, A Shan… - Biochemical …, 2023 - Elsevier
Antimicrobial peptides, as an integral part of the innate immune system, kill bacteria through
a special mechanism of action, making them less susceptible to drug resistance. However …
a special mechanism of action, making them less susceptible to drug resistance. However …
On the silver jubilee of crustacean antimicrobial peptides
GM Matos, RD Rosa - Reviews in Aquaculture, 2022 - Wiley Online Library
Antimicrobial peptides (AMPs) are widely distributed effector molecules that provide a first
line of defence for organisms that lack adaptive immunity, such as crustaceans. They also …
line of defence for organisms that lack adaptive immunity, such as crustaceans. They also …
[HTML][HTML] Antimicrobial Peptides Demonstrate Activity against Resistant Bacterial Pathogens
M Garvey - Infectious Disease Reports, 2023 - mdpi.com
The antimicrobial resistance crisis is an ongoing major threat to public health safety. Low-
and middle-income countries are particularly susceptible to higher fatality rates and the …
and middle-income countries are particularly susceptible to higher fatality rates and the …