Skin infections caused by methicillin-resistant Staphylococcus aureus (MRSA) require the
development of new and effective topical antibiotics. In this context, melittin, the main …

A large number of studies have indicated that Astragalus Membranaceus (AM) possesses
growth-promoting effects in animal husbandry. However, the function of AM in common carp …

An infecting and propagating parasite relies on its innate defense system to evade the host's
immune response and to survive challenges from commensal bacteria. More so for the …

We review the use of molecular dynamics (MD) simulation as a drug design tool in the
context of the role that the lipid membrane can play in drug action, ie, the interaction …

The importance of antibiotics in the treatment of infectious diseases of bacterial origin is well
established. Despite the positive contribution of antibiotics in veterinary and clinical …

Abstract Background Antimicrobial peptides (AMPs) are a diverse class of molecules that
represent a vital part of innate immunity. AMPs are evolutionarily conserved molecules that …

We report herein a new chemical platform for coupling chitosan derivatives to antimicrobial
peptide dendrimers (AMPDs) with different degrees of ramification and molecular weights …

Hypothesis: Most textbook models for antimicrobial peptides (AMP) mode of action are
focused on structural effects and pore formation in lipid membranes, while these …

Microbial resistance is a major concern for public health worldwide, mainly because of the
inappropriate use of antimicrobials. In this scenario, antimicrobial peptides (AMPs) have …

Bacterial infections of the respiratory tract cause millions of deaths annually. Several
diseases exist wherein (1) bacterial infection is the main cause of disease (eg, tuberculosis …