[HTML][HTML] PEGylation enhances the antibacterial and therapeutic potential of amphibian host defence peptides

SR Dennison, SM Reddy, LHG Morton, F Harris… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Abstract Aurein 2.1, aurein 2.6 and aurein 3.1 are amphibian host defence peptides that kill
bacteria via the use of lytic amphiphilic α-helical structures. The C-terminal PEGylation of …

[HTML][HTML] Biomaterial therapeutic strategies for treatment of bacterial lung infections

E Chee, AJ García - Biofilm, 2023 - Elsevier
Bacterial infections of the lung frequently occur as a secondary infection to many respiratory
viral infections and conditions, including influenza, COVID-19, chronic obstructive …

Are antimicrobial peptide dendrimers an escape from ESKAPE?

Y Kawano, O Jordan, T Hanawa, G Borchard… - Advances in wound …, 2020 - liebertpub.com
Significance: The crisis of antimicrobial resistance (AMR) increases dramatically despite all
efforts to use available antibiotics or last resort antimicrobial agents. The spread of the AMR …

Peptides for health benefits 2019

C Martínez-Villaluenga… - International journal of …, 2020 - mdpi.com
In recent years, peptides have received increased interest in pharmaceutical, food,
cosmetics and various other fields. The high potency, specificity and good safety profile are …

Antimicrobial Peptides Demonstrate Activity against Resistant Bacterial Pathogens

M Garvey - Infectious Disease Reports, 2023 - mdpi.com
The antimicrobial resistance crisis is an ongoing major threat to public health safety. Low-
and middle-income countries are particularly susceptible to higher fatality rates and the …

Boosting Membrane Interactions and Antimicrobial Effects of Photocatalytic Titanium Dioxide Nanoparticles by Peptide Coating

L Caselli, E Parra‐Ortiz, S Micciulla, MWA Skoda… - Small, 2024 - Wiley Online Library
Photocatalytic nanoparticles offer antimicrobial effects under illumination due to the
formation of reactive oxygen species (ROS), capable of degrading bacterial membranes …

Peptaibol-Containing Extracts of Trichoderma atroviride and the Fight against Resistant Microorganisms and Cancer Cells

J Víglaš, S Dobiasová, J Viktorová, T Ruml, V Repiská… - Molecules, 2021 - mdpi.com
Fighting resistance to antibiotics and chemotherapeutics has brought bioactive peptides to
the fore. Peptaibols are short α-aminoisobutyric acid-containing peptides produced by …

Antimicrobial Peptides towards Clinical Application—A Long History to Be Concluded

L Cresti, G Cappello, A Pini - International Journal of Molecular Sciences, 2024 - mdpi.com
Antimicrobial peptides (AMPs) are molecules with an amphipathic structure that enables
them to interact with bacterial membranes. This interaction can lead to membrane crossing …

Development of a novel antibacterial peptide, PAM-5, via combination of phage display selection and computer-assisted modification

HL Yuen, SY Chan, YE Ding, S Lim, GC Tan, CL Kho - Biomolecules, 2023 - mdpi.com
Antibacterial peptides (ABPs) have been proposed as potential candidates for alternative
antibacterial agents due to the extensive dissemination of antibiotic resistance. However …

An Enhanced Variant Designed From DLP4 Cationic Peptide Against Staphylococcus aureus CVCC 546

B Li, N Yang, X Wang, Y Hao, R Mao, Z Li… - Frontiers in …, 2020 - frontiersin.org
Insect defensins are promising candidates for the development of potent antimicrobials
against antibiotic-resistant Staphylococcus aureus (S. aureus). An insect defensin, DLP4 …