The placenta is essential for the efficient delivery of nutrients and oxygen from mother to
fetus to maintain normal fetal growth. Dysfunctional placental development underpins many …

Despite the steady increase in the number of studies focusing on the development of tissue
engineered constructs, solutions delivered to the clinic are still limited. Specifically, the lack …

Different blood flow patterns in the arteries can alter the adaptive phenotype of vascular
endothelial cells (ECs), thereby affecting the functions of ECs and are directly associated …

Microfluidic organ-on-a-chip designs are used to mimic human tissues, including the
vasculature. Here we present a novel microfluidic device that allows the interaction of …

STUDY QUESTION What is the physiological extent of vascular remodelling in and
trophoblast plugging of the uterine circulation across the first half of pregnancy? SUMMARY …

The placenta is a unique organ system that functionally combines both maternal and fetal
cell types with distinct lineage origins. Normal placentation is critical for developmental …

Physical activity (PA) has beneficial effects on the function of many organs by modulating
their vascular development. Regular PA during pregnancy is associated with favorable short …

Favouring or thwarting the development of a vascular network is essential in fields as
diverse as oncology, cardiovascular disease or tissue engineering. As a result …

Multi-scale structural assessment of biological soft tissue is challenging but essential to gain
insight into structure–function relationships of tissue/organ. Using the human placenta as an …

Preeclampsia is often preceded by abnormal hemodynamic changes with heterogeneous
patterns in the first half of pregnancy. We assessed the effect of timely tailored correction of …