An emerging body of data suggests that lipid metabolism has an important role to play in the
aging process. Indeed, a plethora of dietary, pharmacological, genetic, and surgical lipid …

Membranous nephropathy (MN) is characterized histomorphologically by the presence of
immune deposits in the subepithelial space of the glomerular filtration barrier; its clinical …

Membranous nephropathy is a major cause of nephrotic syndrome of non-diabetic origin in
adults. It is the second or third leading cause of end-stage renal disease in patients with …

Membranous nephropathy (MN) is a glomerular disease that can occur at all ages. In adults,
it is the most frequent cause of nephrotic syndrome. In~ 80% of patients, there is no …

Idiopathic membranous nephropathy (INM) remains a common cause of the nephrotic
syndrome in adults. The autoimmune nature of IMN was clearly delineated in 2009 with the …

Abstract Phospholipase A 2 receptor 1 (PLA2R) is a target autoantigen in 70% of patients
with idiopathic membranous nephropathy. We describe the location of a major epitope in the …

The phospholipase A2 receptor (PLA2R1) is the major autoantigen in idiopathic
membranous nephropathy. However, the value of anti-PLA2R1 antibody titers in predicting …

Membranous nephropathy (MN) is an autoimmune disease usually associated with a
nephrotic syndrome and it may progress to ESRD in the long term. Its etiology is often …

The discovery in 2009 of the M-type phospholipase A2 receptor (PLA2R) as the primary
target in membranous nephropathy (MN) greatly advanced basic and clinical research …

Lessons from an animal model that faithfully resembles human membranous nephropathy
(MN) have informed our understanding of the pathogenesis of this organ-specific …