Enigma (partially) resolved: phospholipase A2 receptor is the cause of “idiopathic” membranous glomerulonephritis
LD Truong, SV Seshan - American Journal of Physiology …, 2015 - journals.physiology.org
Membranous glomerulonephritis (MGN) is a very significant kidney disease. It is one of the
frequent causes of heavy protein excretion in urine. MGN is thought to be an immune …
frequent causes of heavy protein excretion in urine. MGN is thought to be an immune …
Crystal structure of the CTLD7 domain of human M-type phospholipase A2 receptor
B Yu, Z Hu, D Kong, C Cheng, Y He - Journal of Structural Biology, 2019 - Elsevier
M-type phospholipase A2 receptor (PLA2R) is a member of the mannose receptor family.
Recent evidence shows that PLA2R is a major autoantigen causing idiopathic membranous …
Recent evidence shows that PLA2R is a major autoantigen causing idiopathic membranous …
Anti-phospholipase A2 Receptor Antibody and Immunosuppression in Membranous Nephropathy: More Evidence for Pathogenicity of Anti-phospholipase A: 2 …
PEC Brenchley - Journal of the American Society of Nephrology, 2015 - journals.lww.com
EDITORIALS www. jasn. org with primary membranous nephropathy (MN), 1 our
understanding of the role of anti-PLA2R in clinical disease has evolved rapidly. The initial …
understanding of the role of anti-PLA2R in clinical disease has evolved rapidly. The initial …
Recent advances in the understanding of immune-mediated nephrotic syndrome: diagnostic and prognostic implications
SA Timmermans, P van Paassen… - Expert review of …, 2015 - Taylor & Francis
Glomerular diseases with severe defects in glomerular permeability give rise to heavy
proteinuria and can present as nephrotic syndrome. There are many different causes of the …
proteinuria and can present as nephrotic syndrome. There are many different causes of the …
[HTML][HTML] A Genetic Risk Score Distinguishes Different Types of Autoantibody-Mediated Membranous Nephropathy
Introduction: Membranous nephropathy (MN) is the leading cause of nephrotic syndrome in
adults and is characterized by detectable autoantibodies against glomerular antigens, most …
adults and is characterized by detectable autoantibodies against glomerular antigens, most …
Membranous nephropathy
L Mercadal - Néphrologie & Thérapeutique, 2013 - jle.com
Maladies auto-immunes Lupus érythémateux disséminé, Sjögren, sclérodermie,
dermatomyosite, syndrome des antiphospholipides, polymicroangéite, polyarthrite …
dermatomyosite, syndrome des antiphospholipides, polymicroangéite, polyarthrite …
Interaction between PLA2R1 and HLA‐DQA1 variants contributes to the increased genetic susceptibility to membranous nephropathy in Western China
W Wang, S Fan, G Li, AY Wang, D Hong, X Zhong… - …, 2019 - Wiley Online Library
Aim Recent studies showed that single nucleotide polymorphisms (SNP) within the
phospholipase A2 receptor (PLA2R1) and human leukocyte antigen complex class II HLA …
phospholipase A2 receptor (PLA2R1) and human leukocyte antigen complex class II HLA …
[HTML][HTML] The association between variants in PLA2R and HLA-DQA1 and renal outcomes in patients with primary membranous nephropathy in Western China
S Fan, Q Wang, AY Wang, P Zhang, X Zhong… - BMC Medical …, 2021 - Springer
Abstract Background Both Genome-wide associations and our previous study have shown
that single nucleotide polymorphisms (SNPs) of M-type phospholipase A2 receptor (PLA2R) …
that single nucleotide polymorphisms (SNPs) of M-type phospholipase A2 receptor (PLA2R) …