Vaccination with Sabin, a live attenuated oral polio vaccine (OPV), results in robust intestinal
and humoral immunity and has been key to controlling poliomyelitis. As with any RNA virus …

Poliomyelitis is caused by Poliovirus, a member of a large group of enteroviruses. Vaccine-
derived polioviruses (VDPVs) stem from mutated live poliovirus, which is contained in the …

Comment www. thelancet. com/infection Vol 22 October 2022 1413 decreased surveillance
of acute flaccid paralysis are not addressed with alacrity. 1–3 Detection of vaccine-derived …

Increasing detections of vaccine-derived poliovirus (VDPV) globally, including in countries
previously declared polio free, is a public health emergency of international concern …

Poliomyelitis, a debilitating disease, has been largely eliminated due to the global
dissemination of effective vaccines. The first vaccine against poliovirus, introduced in 1961 …

After 32 years of polio elimination in Peru, six sporadic cases of vaccine-derived poliovirus
(VDPV) have been reported between 2003 and 2011 in urban and periurban settings. On 21 …

The success of the global polio eradication initiative is threatened by the genetic instability of
the oral polio vaccine, which can result in the emergence of pathogenic vaccine-derived …

In 1988, the WHO launched the Global Poliomyelitis Eradication Initiative with the goal of
eradication by 2000. Not only has this goal, which has been repeatedly postponed, still not …

After a long global battle with wild poliovirus, the virus has been defeated through
researches and vaccination using the oral polio vaccine and inactivated polio vaccine as …

Poliomyelitis is an acute communicable disease caused by a singlestranded RNA
enterovirus with 3 serotypes of poliovirus (Type1, 2, 3) causing an irreversible paralytic …