Development of membrane‐active peptide therapeutics in oncology

CH Chen, B Zan, JP Ulmschneider… - Journal of Peptide …, 2023 - Wiley Online Library
Membrane‐active peptides play an essential role in many living organisms and their
immune systems and counter many infectious diseases. Many have dual or multiple …

Review of recent preclinical and clinical research on ligand-targeted liposomes as delivery systems in triple negative breast cancer therapy

M Hajimolaali, FA Dorkoosh… - Journal of Liposome …, 2024 - Taylor & Francis
Triple-negative breast Cancer (TNBC) is one of the deadliest types, making up about 20% of
all breast cancers. Chemotherapy is the traditional manner of progressed TNBC treatment; …

[HTML][HTML] Peptide-Mediated Nanocarriers for Targeted Drug Delivery: Developments and Strategies

Y Wang, L Zhang, C Liu, Y Luo, D Chen - Pharmaceutics, 2024 - mdpi.com
Effective drug delivery is essential for cancer treatment. Drug delivery systems, which can be
tailored to targeted transport and integrated tumor therapy, are vital in improving the …

Recent advances and applications of peptide–agent conjugates for targeting tumor cells

V Alamdari-Palangi, KR Jaberi, M Shahverdi… - Journal of Cancer …, 2023 - Springer
Background Cancer, being a complex disease, presents a major challenge for the scientific
and medical communities. Peptide therapeutics have played a significant role in different …

Anticancer Activity of HER2-targeting CPP-PTEN-THP Chimeric Proteins

E Pioquinto-Avila, AO González-Cruz… - Anticancer …, 2024 - ar.iiarjournals.org
Background/Aim: Protein phosphatase and tensin homolog (PTEN) is a tumor suppressor
protein with potential to be a new biotechnological drug for PTEN-deficient cancer treatment …

Programming an antibody-peptide sandwich procedure for selectivity and ultrasensitive detection of fibrin using double-stranded DNA (dsDNA) hemp string probe

J Zhang, Y Zhang, Y Chen, X Zhao, Y Hao… - Sensors and Actuators B …, 2023 - Elsevier
A novel, highly sensitive and selective sandwich-like enzyme-linked immunoassay
procedure for the detection of fibrin was developed. Firstly the monoclonal anti-fibrinogen …

[HTML][HTML] Investigating the Insertion Mechanism of Cell-Penetrating Peptide Penetratin into Cell Membranes: Implications for Targeted Drug Delivery

B Almarwani, YZ Hamada, N Phambu, A Sunda-Meya - Biophysica, 2023 - mdpi.com
The cell-penetrating peptide (CPP) penetratin (PEN) has garnered attention for its potential
to enter tumor cells. However, its translocation mechanism and lack of selectivity remain …

Interaction Studies of the Peptide G23 with Membrane-Mimetic Systems

RN Nahas - 2022 - search.proquest.com
The prevalence of cancers and neurodegenerative diseases in high-income countries is
devastating to the healthcare system. Many curative drugs exist but cannot get to the site of …