Epstein–Barr virus (EBV) is a ubiquitous human lymphotropic herpesvirus with a well-
established causal role in several cancers. Recent studies have provided compelling …

Human T cells have a diverse T‐cell receptor (TCR) repertoire that endows them with the
ability to identify and defend against a broad spectrum of antigens. The universe of possible …

Autologous hematopoietic stem cell transplantation (aHSCT) is a highly effective treatment
of multiple sclerosis (MS). It depletes autoreactive cells and subsequently renews adaptive …

Autoimmune diseases are a diverse and complex set of chronic disorders with a substantial
impact on patient quality of life and a significant global healthcare burden. Current …

Multiple sclerosis (MS) is a chronic neurodegenerative autoimmune disease, characterised
by the demyelination of neurons in the central nervous system. Whilst it is unclear what …

It is generally accepted that certain viral infections can trigger the development of
autoimmune diseases. However, the exact mechanisms by which these viruses induce …

Multiple sclerosis (MS) is an immune inflammatory disease that causes demyelination of the
white matter of the central nervous system. It is generally accepted that the etiology of MS is …

Multiple sclerosis is an autoimmune inflammatory disease that affects the central nervous
system through chronic demyelination and loss of oligodendrocytes. Since the relapsing …

Current research and drug development for multiple sclerosis (MS) is fully influenced by the
self–nonself (SNS) model of immunity, suggesting that breakage of immunological tolerance …

The 2022 ECTRIMS lecture focused on pediatric-onset multiple sclerosis (POMS), in
recognition of the pivotal importance of prompt recognition and treatment of children and …