Anaemia is a common complication of chronic kidney disease (CKD). In this setting, iron
deficiency is frequent because of the combination of increased iron needs to sustain …

Objective There is widespread agreement about the key role of hemoglobin for oxygen
transport. Both observational and interventional studies have examined the relationship …

This pre-eminent work has developed over six editions in response to man's attempts to
climb higher and higher unaided, and to spend more time at altitude for both work and …

Iron deficiency impairs skeletal muscle metabolism. The underlying mechanisms are
incompletely characterised, but animal and human experiments suggest the involvement of …

Key points Iron acts as a cofactor in the stabilization of the hypoxic‐inducible factor family,
and plays an influential role in the modulation of hypoxic pulmonary vasoconstriction. It is …

Background Increased iron availability modifies cardiorespiratory function in healthy
volunteers and improves exercise capacity and quality of life in patients with heart failure or …

Cerebral blood flow (CBF) increases during hypoxia to counteract the reduction in arterial
oxygen content. The onset of tissue hypoxemia coincides with the stabilization of hypoxia …

Maximal exercise capacity is reduced at altitude or during hypoxia at sea level. It has been
suggested that this might reflect increased right ventricular afterload due to hypoxic …

This commentary refers to 'Pulmonary vascular disease in pulmonary hypertension due to
left heart disease: pathophysiologic implications', by K. Omote et al., https://doi. org/10 …

Purpose Non-anemic iron deficiency (NAID) is common in COPD, and could induce
functional/structural changes in the pulmonary vascular bed. Thus, we aimed to study …