Over the last three decades, polymeric micelles have emerged as a highly promising drug
delivery platform for therapeutic compounds. Particularly, poorly soluble small molecules …

The efficient and selective delivery of therapeutic drugs to the target site remains the main
obstacle in the development of new drugs and therapeutic interventions. Up until today …

Paclitaxel is a diterpenoid pseudoalkaloid, isolated from Taxus brevifolia, and is largely
used as an antitumoral drug. The formulation of paclitaxel known as Taxol® employs a …

Paclitaxel and rapamycin have been reported to act synergistically to treat breast cancer.
Albeit paclitaxel is available for breast cancer treatment, the most commonly used …

The majority of anticancer drugs have poor aqueous solubility, produce adverse effects in
healthy tissue, and thus impose major limitations on both clinical efficacy and therapeutic …

In this study, pH-triggered polymeric micelle comprising α-tocopherol (TOC) and heparin
(HEP) was developed and loaded with docetaxel (DTX). The amphiphilic copolymer was …

Cancer is undeniably a major health risk factor that is growing rapidly globally despite
promising medicinal and pharmaceutical development. Treatment of cancer remains an …

Purpose Poor site-specific delivery and insufficient intracellular drug release in tumors are
inherent disadvantages to successful chemotherapy. In this study, an extraordinary …

Graphene oxide (GO) has shown great potential in drug delivery. However, the aqueous
stability, non-specific drug release and slow release rate are major problems of the GO …

Molecularly imprinted polymers have exhibited good performance as carriers on drug
loading and sustained release. In this paper, vinblastine (VBL)-loaded polymeric …