Radiation-induced oral mucositis (RIOM) is a major dose-limiting toxicity in head and neck
cancer patients. It is a normal tissue injury caused by radiation/radiotherapy (RT), which has …

Most head and neck cancers are squamous cell carcinomas that develop in the upper
aerodigestive epithelium after exposure to carcinogens such as tobacco and alcohol …

Treatment is complex for patients with head and neck (H&N) cancers with specific site of
disease, stage, and pathologic findings guiding treatment decision-making. Treatment …

Abstract Background and purpose The Meta-Analysis of Chemotherapy in squamous cell
Head and Neck Cancer (MACH-NC) demonstrated that concomitant chemotherapy (CT) …

Background We conducted a multinational, randomized study to compare radiotherapy
alone with radiotherapy plus cetuximab, a monoclonal antibody against the epidermal …

Background We compared concomitant cisplatin and irradiation with radiotherapy alone as
adjuvant treatment for stage III or IV head and neck cancer. Methods After undergoing …

Purpose Concurrent chemoradiotherapy (CCRT) for squamous cell carcinoma of the head
and neck (SCCHN) increases both local tumor control and toxicity. This study evaluates …

Purpose: The Head and Neck Intergroup conducted a phase III randomized trial to test the
benefit of adding chemotherapy to radiation in patients with unresectable squamous cell …

Background and purpose: To determine the frequency of mucositis and associated
outcomes in patients receiving radiotherapy (RT) for head and neck cancer through a …

Head and neck cancers include neoplasms of the oral cavity, pharynx, and larynx. The risk
of these cancers is strongly associated with smoking and alcohol ingestion. There have …