Genetic heterogeneity and respiratory chain enzyme analysis in pediatric Indian patients with mitochondrial disorder: Report of novel variants in POLG1 gene and …

D Saha, S Kothari, SD Kulkarni, M Thambiraja… - Mitochondrion, 2024 - Elsevier
Mitochondrial disorders are a heterogeneous group of disorders caused by mutations in the
mitochondrial DNA or in nuclear genes encoding the mitochondrial proteins and subunits …

visGReMLIN: graph mining-based detection and visualization of conserved motifs at 3D protein-ligand interface at the atomic level

VS Ribeiro, CA Santana, AV Fassio, FR Cerqueira… - BMC …, 2020 - Springer
Background Interactions between proteins and non-proteic small molecule ligands play
important roles in the biological processes of living systems. Thus, the development of …

Diameter Is a Key 3D Characteristic for Assessments of Efficient Inhibitors of Protein–Protein Interactions

M Nakadai, S Tomida - Journal of Chemical Information and …, 2020 - ACS Publications
Three-dimensional (3D) molecular descriptors, including physicochemical and shape
properties, for protein–protein interaction (PPI) interface inhibitors have become a topic of …