Advances in Hypoxia-Inducible Factor-1α Stabilizer Deferoxamine in Tissue Engineering
Y Zhu, B Chang, Y Pang, H Wang… - Tissue Engineering Part B …, 2023 - liebertpub.com
Deferoxamine (DFO) is an iron chelator with FDA approval for the clinical treatment of iron
excess. As a well-established stabilizer of hypoxia-inducible factor-1α (HIF-1α), DFO can …
excess. As a well-established stabilizer of hypoxia-inducible factor-1α (HIF-1α), DFO can …
An antibacterial and proangiogenic double-layer drug-loaded microneedle patch for accelerating diabetic wound healing
S Gao, W Zhang, X Zhai, X Zhao, J Wang… - Biomaterials …, 2023 - pubs.rsc.org
Diabetic wounds are difficult to heal because of bacterial infections and insufficient
angiogenesis. Herein, we report a double-layer drug-loaded microneedle patch with …
angiogenesis. Herein, we report a double-layer drug-loaded microneedle patch with …
Nanoscale metal–organic frameworks as smart nanocarriers for cancer therapy
Y Liu, P Lei, X Liao, C Wang - Journal of Nanostructure in Chemistry, 2024 - Springer
Cancer is one of the serious diseases to human life. Early and precise cancer diagnosis and
timely therapy are in urgent need nowadays. Due to the advantages of porous structures …
timely therapy are in urgent need nowadays. Due to the advantages of porous structures …
Bioactive fish scale scaffolds with MSCs‐loading for skin flap regeneration
Skin flap transplantations are common methods for covering and repairing tissue defects in
surgery, while the survival rates of these skin flaps are still low due to the vascular crisis and …
surgery, while the survival rates of these skin flaps are still low due to the vascular crisis and …
Macroporous silk nanofiber cryogels with tunable properties
X Zhang, Y Hang, Z Ding, L Xiao, W Cheng… - …, 2022 - ACS Publications
Cryogels are widely used in tissue regeneration due to their porous structures and friendly
hydrogel performance. Silk-based cryogels were developed but failed to exhibit desirable …
hydrogel performance. Silk-based cryogels were developed but failed to exhibit desirable …
[HTML][HTML] Chelating the valley of death: Deferoxamine's path from bench to wound clinic
JB Parker, MF Griffin, MA Downer, D Akras… - Frontiers in …, 2023 - frontiersin.org
There is undisputable benefit in translating basic science research concretely into clinical
practice, and yet, the vast majority of therapies and treatments fail to achieve approval. The …
practice, and yet, the vast majority of therapies and treatments fail to achieve approval. The …
Silk Nanocarrier size optimization for enhanced tumor cell penetration and cytotoxicity in vitro
L Xiao, Z Ding, X Zhang, X Wang, Q Lu… - … Science & Engineering, 2021 - ACS Publications
Silk nanofibers are versatile carriers for hydrophobic and hydrophilic drugs, but fall short in
terms of effective delivery to cells, which is essential for therapeutic benefits. Here, the size …
terms of effective delivery to cells, which is essential for therapeutic benefits. Here, the size …
A tea polyphenol-loaded cellulose/silk fibroin/polyacrylic acid hydrogel for wound healing
H Liu, L Chen, Y Peng, X Li, H Zhang, Y Chen, Z Li… - Cellulose, 2024 - Springer
Hydrogels can relieve wound pain and provide a moist environment for wound healing.
Although hydrogels based on natural materials have proven to be biocompatible and …
Although hydrogels based on natural materials have proven to be biocompatible and …
Silk Nanofiber Carriers for Both Hydrophilic and Hydrophobic Drugs to Achieve Improved Combination Chemotherapy
L Xiao, H Yang, Q Lu, DL Kaplan - Macromolecular Bioscience, 2024 - Wiley Online Library
Combination chemotherapy is considered an effective strategy to inhibit tumor growth. Here,
beta‐sheet‐rich silk nanofibers are co‐loaded with hydrophilic doxorubicin (DOX) and …
beta‐sheet‐rich silk nanofibers are co‐loaded with hydrophilic doxorubicin (DOX) and …
[HTML][HTML] Calycosin increases random-pattern skin flap survival by activating TFEB-mediated regulation of cell death
R Jiang, X Chen, K Wang, K Fu, C Dong, Z Chen… - Journal of Functional …, 2024 - Elsevier
Random-pattern skin flaps play a vital role in repairing and reconstructing soft tissue defects.
Clinical utilization of skin flaps is limited due to distal necrosis. Calycosin (CAL) is an …
Clinical utilization of skin flaps is limited due to distal necrosis. Calycosin (CAL) is an …