Therapeutic siRNA: state of the art
ABSTRACT RNA interference (RNAi) is an ancient biological mechanism used to defend
against external invasion. It theoretically can silence any disease-related genes in a …
against external invasion. It theoretically can silence any disease-related genes in a …
RNAi therapeutic and its innovative biotechnological evolution
Abstract Recently, United States Food and Drug Administration (FDA) and European
Commission (EC) approved Alnylam Pharmaceuticals' RNA interference (RNAi) therapeutic …
Commission (EC) approved Alnylam Pharmaceuticals' RNA interference (RNAi) therapeutic …
Advances in microfluidic strategies for single-cell research
Y Liu, Z Fan, L Qiao, B Liu - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
A core challenge in biomedical and life science research is to decipher cell-to-cell
differences under pathological progression or external perturbation. Microfluidics-based …
differences under pathological progression or external perturbation. Microfluidics-based …
Viral Protein‐Pseudotyped and siRNA‐Electroporated Extracellular Vesicles for Cancer Immunotherapy
H Liu, L Huang, M Mao, J Ding, G Wu… - Advanced Functional …, 2020 - Wiley Online Library
Extracellular vesicles (EVs) have shown great potential in drug delivery, disease diagnosis,
and treatment owing to their versatile native features and functions. RNA interference (RNAi) …
and treatment owing to their versatile native features and functions. RNA interference (RNAi) …
ROS-activatable siRNA-engineered polyplex for NIR-triggered synergistic cancer treatment
Small interfering RNA (siRNA) shows excellent pharmaceutical prospects in treating diverse
life-threatening diseases. Photodynamic therapy (PDT) is a clinically employed noninvasive …
life-threatening diseases. Photodynamic therapy (PDT) is a clinically employed noninvasive …
The international society of RNA nanotechnology and nanomedicine (ISRNN): the present and future of the burgeoning field
M Chandler, B Johnson, E Khisamutdinov… - ACS …, 2021 - ACS Publications
The International Society of RNA Nanotechnology and Nanomedicine (ISRNN) hosts an
annual meeting series focused on presenting the latest research achievements involving …
annual meeting series focused on presenting the latest research achievements involving …
Microneedles in advanced microfluidic systems: A systematic review throughout lab and organ-on-a-chip applications
Microneedles (MNs) have been widely used in biomedical applications for drug delivery and
biomarker detection purposes. Furthermore, MNs can also be used as a stand-alone tool to …
biomarker detection purposes. Furthermore, MNs can also be used as a stand-alone tool to …
Recent advances on fabrication of microneedles on the flexible substrate
Microneedles are able to penetrate into the skin and offer great chances in various
biomedical applications including transdermal drug delivery, stable bio-signal monitoring …
biomedical applications including transdermal drug delivery, stable bio-signal monitoring …
Recent advances in nanocomposite-based delivery systems for targeted CRISPR/Cas delivery and therapeutic genetic manipulation
CRISPR/Cas systems are novel gene editing tools with tremendous capacity and accuracy
for gene editing and hold great potential for therapeutic genetic manipulation. However, the …
for gene editing and hold great potential for therapeutic genetic manipulation. However, the …
Combinatorial physical methods for cellular therapy: towards the future of cellular analysis?
The physical energy activated techniques for cellular delivery and analysis is one of the
most rapidly expanding research areas for a variety of biological and biomedical …
most rapidly expanding research areas for a variety of biological and biomedical …