In the forensic medicine field, molecular autopsy is the post-mortem genetic analysis
performed to attempt to unravel the cause of decease in cases remaining unexplained after …

Pediatric cardiomyopathies (CMs) and electrical diseases constitute a heterogeneous
spectrum of disorders distinguished by structural and electrical abnormalities in the heart …

The diffusion of next-generation sequencing (NGS)-based approaches allows for the
identification of pathogenic mutations of cardiomyopathies and channelopathies in more …

Sudden death cases in the young population remain without a conclusive cause of decease
in almost 40% of cases. In these situations, cardiac arrhythmia of genetic origin is suspected …

Sudden cardiac death (SCD) in children is a devastating event, often linked to primary
electrical diseases (PED) of the heart. PEDs, often referred to as channelopathies, are a …

Sudden cardiac death (SCD) is defined as unexpected death due to a cardiac cause that
occurs rapidly. Despite the identification of prevention strategies, SCD remains a serious …

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare inherited cardiac
ion channelopathy where the initial disease presentation is during childhood or adolescent …

Background: Fetal bradycardia is a common but severe condition. In addition to autoimmune-
mediated fetal heart block, several types of channelopathies induce high-degree …

Background Among all fetal heart block patients,> 50% cases are associated with maternal
autoimmune diseases, and such patients should receive treatment. However, nearly half of …

Short QT syndrome (SQTS) is an extremely rare inherited arrhythmogenic entity. Nowadays,
less than 200 families affected worldwide have been reported. This syndrome is …