Molecular targets on mast cells and basophils for novel therapies
IT Harvima, F Levi-Schaffer, P Draber… - Journal of Allergy and …, 2014 - Elsevier
Mast cells and basophils (MCs/Bs) play a crucial role in type I allergy, as well as in innate
and adaptive immune responses. These cells mediate their actions through soluble …
and adaptive immune responses. These cells mediate their actions through soluble …
[HTML][HTML] The expression and function of CD300 molecules in the main players of allergic responses: mast cells, basophils and eosinophils
J Vitallé, I Terrén, A Orrantia, A Bilbao… - International journal of …, 2020 - mdpi.com
Allergy is the host immune response against non-infectious substances called allergens.
The prevalence of allergic diseases is increasing worldwide. However, while some drugs …
The prevalence of allergic diseases is increasing worldwide. However, while some drugs …
A novel bispecific DARP in targeting Fcγ RIIB and Fcε RI‐bound IgE inhibits allergic responses
F Zellweger, P Gasser, D Brigger, P Buschor, M Vogel… - Allergy, 2017 - Wiley Online Library
Background Binding of allergen‐specific IgE to its high‐affinity receptor Fcε RI on basophils
and mast cells is a central event in the development of allergies. Exposure of these cells to …
and mast cells is a central event in the development of allergies. Exposure of these cells to …
A critical role for IL-18 in transformation and maturation of naive eosinophils to pathogenic eosinophils
SU Venkateshaiah, A Mishra, M Manohar… - Journal of Allergy and …, 2018 - jacionline.org
1. Jartti T, van den Hoogen B, Garofalo RP, Osterhaus AD, Ruuskanen O. Metapneumovirus
and acute wheezing in children. Lancet 2002; 360: 1393-4. 2. Williams JV, Harris PA …
and acute wheezing in children. Lancet 2002; 360: 1393-4. 2. Williams JV, Harris PA …
New opportunities for allergen immunotherapy using synthetic peptide immuno-regulatory epitopes (SPIREs)
L Klimek, O Pfaar, M Worm - Expert review of clinical immunology, 2016 - Taylor & Francis
Introduction: Allergen immunotherapy (AIT) reduces allergic rhinoconjunctivitis (ARC)
symptoms, but long-term efficacy requires treatment for 3–5 years. Synthetic peptide immuno …
symptoms, but long-term efficacy requires treatment for 3–5 years. Synthetic peptide immuno …
[HTML][HTML] Systematic Characterization of the Group 2 House Dust Mite Allergen in Dermatophagoides microceras
RH Hu, CT Wu, TS Wu, FY Yu, JL Ko… - Frontiers in cellular and …, 2022 - frontiersin.org
Background Allergic asthma, a chronic airway inflammatory disease, is a critical public
health problem. Indoor house dust mites (HDMs) could cause allergic asthma. The …
health problem. Indoor house dust mites (HDMs) could cause allergic asthma. The …
Development of a hollow mesoporous silica nanoparticles vaccine to protect against house dust mite induced allergic inflammation
X Peng, Y Liang, Y Yin, H Liao, L Li - International Journal of Pharmaceutics, 2018 - Elsevier
Allergen specific immunotherapy (SIT) is the only specific therapeutic way for house dust
mite (HDM) allergy. To improve the efficacy of SIT, hollow mesoporous silica nanoparticles …
mite (HDM) allergy. To improve the efficacy of SIT, hollow mesoporous silica nanoparticles …
House dust mite allergen Der f 2 induces interleukin-13 expression by activating the PI3K/Akt pathway
EJ Ro, PH Cha, HY Kim, YH Cho, JW Park, JS Han… - Immunologic …, 2013 - Springer
House dust mites (HDMs) are a common cause of allergic asthma. The group 2 allergen
from Dermatophagoides farinae, Der f 2, is one of the major HDM allergens. Elevated Der f 2 …
from Dermatophagoides farinae, Der f 2, is one of the major HDM allergens. Elevated Der f 2 …
[HTML][HTML] Low-molecular-weight heparin and unfractionated heparin decrease Th-1, 2, and 17 expressions
JN Huang, MC Tsai, SL Fang, MDT Chang, YR Wu… - PLoS …, 2014 - journals.plos.org
Background We evaluated the effects of T helper cell differentiation in a mite-allergic animal
model treated with inhaled heparins of different molecular weight. Method BALB/c mice were …
model treated with inhaled heparins of different molecular weight. Method BALB/c mice were …
Immunotheraphy in allergic diseases
A Roger, M Basagana, A Teniente-Serra… - Current …, 2018 - ingentaconnect.com
The prevalence of allergic diseases is increasing worldwide. It is estimated that more than
30% of the world population is now affected by one or more allergic conditions and a high …
30% of the world population is now affected by one or more allergic conditions and a high …