Soluble CTLA-4 attenuates T cell activation and modulates anti-tumor immunity

PT Kennedy, EL Saulters, AD Duckworth, YJ Lim… - Molecular Therapy, 2024 - cell.com
CTLA-4 is a crucial immune checkpoint receptor involved in the maintenance of immune
homeostasis, tolerance, and tumor control. Antibodies targeting CTLA-4 have been …

Regulatory T Cells for Control of Autoimmunity

R Kawakami, S Sakaguchi - Basic Immunology and Its Clinical Application, 2024 - Springer
Regulatory T (Treg) cells, which specifically express the master transcription factor FoxP3,
are indispensable for the maintenance of immunological self-tolerance and homeostasis …