[HTML][HTML] Non-coding RNA-mediated modulation of ferroptosis in cardiovascular diseases

Y Liu, W Ding, J Wang, X Ao, J Xue - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Cardiovascular disease (CVD) is a major contributor to increasing morbidity and mortality
worldwide and seriously threatens human health and life. Cardiomyocyte death is …

Maresin1 suppresses high-glucose-induced ferroptosis in osteoblasts via NRF2 activation in type 2 diabetic osteoporosis

Z Zhang, C Ji, YN Wang, S Liu, M Wang, X Xu, D Zhang - Cells, 2022 - mdpi.com
Maresin1 (MaR1) is an endogenous pro-resolving lipid mediator produced from
polyunsaturated fatty acids and is believed to have antioxidant and anti-inflammatory …

Astaxanthin attenuates ferroptosis via Keap1-Nrf2/HO-1 signaling pathways in LPS-induced acute lung injury

L Luo, F Huang, S Zhong, R Ding, J Su, X Li - Life Sciences, 2022 - Elsevier
Ferroptosis is a form of regulated nonapoptotic cell death associated with iron-dependent
lipid peroxidation. Previous studies have shown that ferroptosis is involved in the occurrence …

[HTML][HTML] FUNDC1 interacts with GPx4 to govern hepatic ferroptosis and fibrotic injury through a mitophagy-dependent manner

Y Bi, S Liu, X Qin, M Abudureyimu, L Wang… - Journal of Advanced …, 2024 - Elsevier
Introduction Liver fibrosis is a life-threatening pathological anomaly which usually evolves
into advanced liver cirrhosis and hepatocellular carcinoma although limited therapeutic …

Artemisitene alters LPS-induced oxidative stress, inflammation and ferroptosis in liver through Nrf2/HO-1 and NF-kB pathway

C Zhao, C Xiao, S Feng, J Bai - Frontiers in pharmacology, 2023 - frontiersin.org
The liver plays a critical role in sepsis, which is a serious worldwide public health problem. A
novel mechanism of controlled cell death called ferroptosis has recently been described …

Targeting ferroptosis holds potential for intervertebral disc degeneration therapy

J Chen, X Yang, Y Feng, Q Li, J Ma, L Wang, Z Quan - Cells, 2022 - mdpi.com
Intervertebral disc degeneration (IVDD) is a common pathological condition responsible for
lower back pain, which can significantly increase economic and social burdens. Although …

The emerging roles of ferroptosis in organ fibrosis and its potential therapeutic effect

X Huang, Y Song, L Wei, J Guo, W Xu, M Li - International …, 2023 - Elsevier
Fibrosis refers to the process of excessive deposition of extracellular matrix (ECM) proteins,
eventually leading to excessive scar formation. Fibrotic diseases can occur in many organs …

Polystyrene nanoplastics-induced lung apoptosis and ferroptosis via ROS-dependent endoplasmic reticulum stress

Q Wu, C Liu, D Liu, Y Wang, H Qi, X Liu… - Science of The Total …, 2024 - Elsevier
It has been shown that exposure to nanoplastics (MNPs) through inhalation can induce
pulmonary toxicity, but the toxicological mechanism of MNPs on the respiratory system …

[HTML][HTML] FGF4 improves hepatocytes ferroptosis in autoimmune hepatitis mice via activation of CISD3

H Jiang, Y Fang, Y Wang, T Li, H Lin, J Lin… - International …, 2023 - Elsevier
Autoimmune hepatitis (AIH) is increasingly affecting human health but pharmacotherapies
remain to be identified. Growing evidence reveals that ferroptosis, a newly recognized form …

Retinoic acid protects against lipopolysaccharide-induced ferroptotic liver injury and iron disorders by regulating Nrf2/HO-1 and RARβ signaling

X Lai, A Wu, Y Bing, Y Liu, J Luo, H Yan… - Free Radical Biology …, 2023 - Elsevier
Acute liver injury (ALI) can progress to severe liver diseases, making its prevention and
treatment a focus of research. Retinoic acid (RA) has been shown to have anti-oxidative and …