Ferritinophagy: A new idea for liver diseases regulated by ferroptosis

ZB Qian, JF Li, WY Xiong, XR Mao - Hepatobiliary & Pancreatic Diseases …, 2023 - Elsevier
Background: The discovery of regulatory cell death has led to a breakthrough in the
therapeutic field. Various forms of cell death, such as necrosis, apoptosis, pyroptosis …

Second generation androgen receptor antagonist, TQB3720 abrogates prostate cancer growth via AR/GPX4 axis activated ferroptosis

Z Zhang, T Xie, S Zhang, H Yin, X Zhang… - Frontiers in …, 2023 - frontiersin.org
Purpose: Prostate cancer (PCa) poses a great threat to humans. The study aimed to
evaluate the potential of TQB3720 in promoting ferroptosis to suppress prostate cancer …

Optimization of enzyme-assisted microwave extraction, structural characterization, antioxidant activity and in vitro protective effect against H2O2-induced damage in …

H Chen, Z Bai, S Tao, M Li, L Jian, Y Zhang… - International Journal of …, 2024 - Elsevier
In this study, an enzyme-assisted microwave extraction process was obtained by response
surface method of polysaccharide from roots of Rubus crataegifolius Bunge. The optimized …

[HTML][HTML] Maresins as novel anti-inflammatory actors and putative therapeutic targets in sepsis

Y Sun, S Sun, P Chen, Y Dai, D Yang, Y Lin… - Pharmacological …, 2024 - Elsevier
Sepsis, a complex clinical syndrome characterized by an exaggerated host response to
infection, often necessitates hospitalization and intensive care unit admission. Delayed or …

Melatonin regulates the antioxidant capacity of sheep granulosa cells through a novel uORF-Nrf2aa mediated Nrf2/KEAP1 pathway

J Ma, L Liu, H Yang, Y Wan, Y Zhang, F Wang - Life Sciences, 2024 - Elsevier
Ovarian dysfunction stands as a prevalent contributor to female infertility, with its etiology
intertwined with genetic, autoimmune, and environmental factors. Within the ovarian follicles …

Cynarin alleviates acetaminophen-induced acute liver injury through the activation of Keap1/Nrf2-mediated lipid peroxidation defense via the AMPK/SIRT3 signaling …

L Zhao, X Zhang, Z Chen, Y Lai, J Xu, R Zhou, P Ma… - Food & Function, 2024 - pubs.rsc.org
Overdose of Acetaminophen (APAP) is a major contributor to acute liver injury (ALI), a
complex pathological process with limited effective treatments. Emerging evidence links lipid …

Attenuates reactive oxygen species: induced pyroptosis via activation of the Nrf2/HO-1 signal pathway in models of trigeminal neuralgia

M Liu, Y Wang, S Li, X Hou, T Li, Z Xu, F Chen… - Scientific Reports, 2023 - nature.com
In this study, we examined the impact of demyelinating and neuroinflammation on trigeminal
neuralgia (TN) by utilizing models of chronic constriction injury to the infraorbital nerve (CCI) …

Therapeutic potential of dihydroartemisinin in mitigating radiation‐induced lung injury: Inhibition of ferroptosis through Nrf2/HO‐1 pathways in mice

X Ning, W Zhao, Q Wu, C Wang… - Immunity, Inflammation …, 2024 - Wiley Online Library
Background Radiation‐induced lung injury (RILI) is a common consequence of thoracic
radiation therapy that lacks effective preventative and treatment strategies …

Subacute exposure to black phosphorus quantum dots induces cardiac fibrosis and the potential role of gut microbiota

J Han, F Ruan, C Yang, Z Zuo, Z Liu, C He - Journal of Environmental …, 2025 - Elsevier
Black phosphorus quantum dots (BPQDs) have been used as the nano-carrier in the field of
biomedicine due to their excellent electronic conductivity, optical and thermoelectric …

Water extract of earthworms mitigates mouse liver fibrosis by potentiating hepatic LKB1/Nrf2 axis to inhibit HSC activation and hepatocyte death

T Zhang, C Wang, A Song, X Lei, G Li, H Sun… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance When left untreated, liver fibrosis (LF) causes various
chronic liver diseases. Earthworms (Pheretima aspergillum) are widely used in traditional …