Therapeutic potential of dihydroartemisinin in mitigating radiation‐induced lung injury: Inhibition of ferroptosis through Nrf2/HO‐1 pathways in mice

X Ning, W Zhao, Q Wu, C Wang… - Immunity, Inflammation …, 2024 - Wiley Online Library
Background Radiation‐induced lung injury (RILI) is a common consequence of thoracic
radiation therapy that lacks effective preventative and treatment strategies …

Subacute exposure to black phosphorus quantum dots induces cardiac fibrosis and the potential role of gut microbiota

J Han, F Ruan, C Yang, Z Zuo, Z Liu, C He - Journal of Environmental …, 2025 - Elsevier
Black phosphorus quantum dots (BPQDs) have been used as the nano-carrier in the field of
biomedicine due to their excellent electronic conductivity, optical and thermoelectric …

Water extract of earthworms mitigates mouse liver fibrosis by potentiating hepatic LKB1/Nrf2 axis to inhibit HSC activation and hepatocyte death

T Zhang, C Wang, A Song, X Lei, G Li, H Sun… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance When left untreated, liver fibrosis (LF) causes various
chronic liver diseases. Earthworms (Pheretima aspergillum) are widely used in traditional …

APOC1 reduced anti-PD-1 immunotherapy of nonsmall cell lung cancer via the transformation of M2 into M1 macrophages by ferroptosis by NRF2/HO-1

L Mei, J Long, S Wu, M Mei, D Mei, H Qiu - Anti-Cancer Drugs, 2024 - journals.lww.com
The treatment strategy for nonsmall cell lung cancer (NSCLC) has always been a hot topic of
concern, and its treatment strategies are also emerging. This experiment wants to know the …

[HTML][HTML] Potential therapies for HCC involving targeting the ferroptosis pathway

D Li, M Zhang, J Liu, Z Li, B Ni - American Journal of Cancer …, 2024 - ncbi.nlm.nih.gov
Liver cancer ranks as the third leading cause of cancer-related mortality worldwide,
predominantly in the form of hepatocellular carcinoma (HCC). Conventional detection and …

Ferroptosis: A New Strategy for Targeting Alzheimer's Disease

RR Qiang, Y Xiang, L Zhang, XY Bai, D Zhang… - Neurochemistry …, 2024 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by a complex
pathogenesis, which involves the formation of amyloid plaques and neurofibrillary tangles …

Effects of terbuthylazine on myocardial oxidative stress and ferroptosis via Nrf2/HO-1 signaling pathway in broilers

H Wu, H Li, H Huo, X Li, H Zhu, L Zhao, J Liao… - Pesticide Biochemistry …, 2023 - Elsevier
Terbuthylazine (TBA) is one of the most commonly used and effective herbicides. However,
due to its affinity for soil organic matter and water solubility, TBA can lead to biological health …

[HTML][HTML] New insights into fibrotic signaling in hepatocellular carcinoma

L Shan, F Wang, W Xue, D Zhai, J Liu, X Lv - Frontiers in Oncology, 2023 - frontiersin.org
Hepatocellular carcinoma (HCC) mostly occurs in the background of liver fibrosis, and
activated hepatic stellate cells (HSCs) exist in HCC tissues and adjacent tissues. HSC …

Endotoxin tolerance ameliorates lipopolysaccharide/D-galactosamine-induced acute liver failure by negative regulation of the NF-κB/NLRP3 and activation of Nrf2/HO …

H Shi, X Xie, S Zheng, H Chen, C Liu, S Li… - International …, 2024 - Elsevier
Acute liver failure (ALF) is a potentially fatal disorder characterized by extensive hepatocyte
necrosis and rapid decline in liver function. Numerous factors, including oxidative stress, cell …

[HTML][HTML] Hypermethylation of the glutathione peroxidase 4 promoter predicts poor prognosis in patients with hepatitis B virus-associated acute-on-chronic liver failure

X Su, LY Han, J Wang, Y Zhang, PY Luo… - Frontiers in Molecular …, 2024 - frontiersin.org
Background Hepatitis B virus-associated acute-on-chronic liver failure (HBV-ACLF) is a syn-
drome with a high short-term mortality rate, and its prognosis is critical in clinical …