Epigallocatechin 3-gallate: From green tea to cancer therapeutics
Abstract Epigallocatechin 3-gallate (EGCG) possesses various biological functions,
including anti-cancer and anti-inflammatory properties. EGCG is an abundant polyphenolic …
including anti-cancer and anti-inflammatory properties. EGCG is an abundant polyphenolic …
[HTML][HTML] Angiogenesis in breast cancer progression, diagnosis, and treatment
CO Madu, S Wang, CO Madu, Y Lu - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
Angiogenesis is a significant event in a wide range of healthy and diseased conditions. This
process frequently involves vasodilation and an increase in vascular permeability …
process frequently involves vasodilation and an increase in vascular permeability …
Adipose tissue remodeling and obesity
K Sun, CM Kusminski, PE Scherer - The Journal of clinical …, 2011 - Am Soc Clin Investig
To fulfill its role as the major energy-storing tissue, adipose has several unique properties
that cannot be seen in any other organ, including an almost unlimited capacity to expand in …
that cannot be seen in any other organ, including an almost unlimited capacity to expand in …
Rational approaches, design strategies, structure activity relationship and mechanistic insights for anticancer hybrids
A Hybrid drug which comprises the incorporation of two drug pharmacophores in one single
molecule are basically designed to interact with multiple targets or to amplify its effect …
molecule are basically designed to interact with multiple targets or to amplify its effect …
Central role of oxidative stress in age‐related macular degeneration: evidence from a review of the molecular mechanisms and animal models
Age‐related macular degeneration (AMD) is a common cause of visual impairment in the
elderly. There are very limited therapeutic options for AMD with the predominant therapies …
elderly. There are very limited therapeutic options for AMD with the predominant therapies …
Dichotomous effects of VEGF-A on adipose tissue dysfunction
K Sun, IW Asterholm, CM Kusminski… - Proceedings of the …, 2012 - National Acad Sciences
Obese fat pads are frequently undervascularized and hypoxic, leading to increased fibrosis,
inflammation, and ultimately insulin resistance. We hypothesized that VEGF-A–induced …
inflammation, and ultimately insulin resistance. We hypothesized that VEGF-A–induced …
Perspective of Fe3O4 Nanoparticles Role in Biomedical Applications
In recent years, although many review articles have been presented about bioapplications of
magnetic nanoparticles by some research groups with different expertise such as chemistry …
magnetic nanoparticles by some research groups with different expertise such as chemistry …
Endothelial cell functions
C Michiels - Journal of cellular physiology, 2003 - Wiley Online Library
Endothelial cells play a wide variety of critical roles in the control of vascular function.
Indeed, since the early 1980s, the accumulating knowledge of the endothelial cell structure …
Indeed, since the early 1980s, the accumulating knowledge of the endothelial cell structure …
Matrix metalloproteinases and angiogenesis
JE Rundhaug - Journal of cellular and molecular medicine, 2005 - Wiley Online Library
Matrix metalloproteinases (MMPs) are a family of enzymes that proteolytically degrade
various components of the extracellular matrix (ECM). Angiogenesis is the process of …
various components of the extracellular matrix (ECM). Angiogenesis is the process of …
Natural products in cancer chemotherapy: past, present and future
J Mann - Nature Reviews Cancer, 2002 - nature.com
Natural products have been the mainstay of cancer chemotherapy for the past 30 years.
However, the quickening pace of (aberrant) gene identification, and the new technologies of …
However, the quickening pace of (aberrant) gene identification, and the new technologies of …