Frailty is intertwined with heart failure: mechanisms, prevalence, prognosis, assessment, and management

A Pandey, D Kitzman, G Reeves - JACC: Heart Failure, 2019 - jacc.org
Frailty, a syndrome characterized by an exaggerated decline in function and reserve of
multiple physiological systems, is common in older patients with heart failure (HF) and is …

Multimorbidity in older adults with cardiovascular disease

DE Forman, MS Maurer, C Boyd, R Brindis… - Journal of the American …, 2018 - jacc.org
Multimorbidity occurs in adults of all ages, but the number and complexity of comorbid
conditions commonly increase with advancing age such that cardiovascular disease (CVD) …

[HTML][HTML] Semaglutide in patients with heart failure with preserved ejection fraction and obesity

MN Kosiborod, SZ Abildstrøm, BA Borlaug… - … England Journal of …, 2023 - Mass Medical Soc
Background Heart failure with preserved ejection fraction is increasing in prevalence and is
associated with a high symptom burden and functional impairment, especially in persons …

The SGLT2 inhibitor dapagliflozin in heart failure with preserved ejection fraction: a multicenter randomized trial

ME Nassif, SL Windsor, BA Borlaug, DW Kitzman… - Nature medicine, 2021 - nature.com
Patients with heart failure and preserved ejection fraction (HFpEF) have a high burden of
symptoms and functional limitations, and have a poor quality of life. By targeting …

Physical rehabilitation for older patients hospitalized for heart failure

DW Kitzman, DJ Whellan, P Duncan… - … England Journal of …, 2021 - Mass Medical Soc
Background Older patients who are hospitalized for acute decompensated heart failure have
high rates of physical frailty, poor quality of life, delayed recovery, and frequent …

Cardiorespiratory fitness and mortality risk across the spectra of age, race, and sex

P Kokkinos, C Faselis, IBH Samuel, A Pittaras… - Journal of the American …, 2022 - jacc.org
Background Cardiorespiratory fitness (CRF) is inversely associated with all-cause mortality.
However, the association of CRF and mortality risk for different races, women, and elderly …

Multidisciplinary cardiac rehabilitation and long-term prognosis in patients with heart failure

K Kamiya, Y Sato, T Takahashi… - Circulation: Heart …, 2020 - Am Heart Assoc
Background: Exercise-based cardiac rehabilitation (CR) improves health-related quality of
life and exercise capacity in patients with heart failure (HF). However, CR efficacy in patients …

Effects and costs of real-time cardiac telerehabilitation: randomised controlled non-inferiority trial

R Maddison, JC Rawstorn, RAH Stewart, J Benatar… - Heart, 2019 - heart.bmj.com
Objective Compare the effects and costs of remotely monitored exercise-based cardiac
telerehabilitation (REMOTE-CR) with centre-based programmes (CBexCR) in adults with …

Supervised exercise training for chronic heart failure with preserved ejection fraction: a scientific statement from the American Heart Association and American College …

V Sachdev, K Sharma, SJ Keteyian, CF Alcain… - Circulation, 2023 - Am Heart Assoc
Heart failure with preserved ejection fraction (HFpEF) is one of the most common forms of
heart failure; its prevalence is increasing, and outcomes are worsening. Affected patients …

Exercise in cirrhosis: translating evidence and experience to practice

P Tandon, KP Ismond, K Riess, A Duarte-Rojo… - Journal of …, 2018 - Elsevier
Physical inactivity, sarcopenia, and frailty are highly prevalent, independent predictors of
morbidity and mortality in patients with cirrhosis. Across a range of chronic diseases …