The progressive decline and eventual loss of islet β-cell function underlies the
pathophysiological mechanism of the development of both type 1 and type 2 diabetes …

Background Nestin is an intermediate filament first reported in neuroepithelial stem cells.
Nestin expression could be found in a variety of tissues throughout all systems of the body …

Cardiomyopathy and pancreatic injury are health issues associated with type 2 diabetes
mellitus (T2DM) and are characterized by elevated oxidative stress, inflammation and …

Mesenchymal stem cells (MSCs) are capable of differentiating into other cell types and
exhibit immunomodulatory effects. MSCs are affected by several intrinsic and extrinsic …

Background Diabetes mellitus (DM) is a chronic metabolic disorder, increasing in the
number of patients and poses a severe threat to human health. Significant advances have …

Chordoma is an extremely rare malignant bone tumor with a high rate of relapse. While
cancer stem cells (CSCs) are closely associated with tumor recurrence, which depend on its …

Melatonin interacts with various types of stem cells, in multiple ways that comprise
stimulation of proliferation, maintenance of stemness and self-renewal, protection of survival …

As a pluripotent cell, activated pancreatic stellate cells (PSCs) can differentiate into various
pancreatic parenchymal cells and participate in the secretion of extracellular matrix and the …

Amniotic fluid-derived mesenchymal stromal cells (AFMSCs) present different features,
depending on the isolation timing and culture conditions. The lack of uniform experimental …

Melatonin, a hormone produced in the pineal gland, has been investigated for bone repair,
remodeling, osteoporosis, as well as osseointegration of the implants. In this study, different …