Plasma gradient of soluble urokinase-type plasminogen activator receptor is linked to pathogenic plasma proteome and immune transcriptome and stratifies outcomes …
J Sarif, D Raychaudhuri, R D'Rozario… - Frontiers in …, 2021 - frontiersin.org
Disease caused by SARS-CoV-2 coronavirus (COVID-19) led to significant morbidity and
mortality worldwide. A systemic hyper-inflammation characterizes severe COVID-19 …
mortality worldwide. A systemic hyper-inflammation characterizes severe COVID-19 …
Inflammation‐Related Patterns in the Clinical Staging and Severity Assessment of Chronic Kidney Disease
Chronic kidney disease (CKD) is an irreversible loss of kidney function, and it represents a
major global public health burden due to both its prevalence and its continuously increasing …
major global public health burden due to both its prevalence and its continuously increasing …
A transcriptomics study of hereditary angioedema attacks
Background Hereditary angioedema (HAE) caused by C1-inhibitor deficiency is a lifelong
illness characterized by recurrent acute attacks of localized skin or mucosal edema …
illness characterized by recurrent acute attacks of localized skin or mucosal edema …
A Urokinase receptor–derived peptide inhibiting VEGF-dependent directional migration and vascular sprouting
K Bifulco, I Longanesi-Cattani, E Liguori, C Arra… - Molecular cancer …, 2013 - AACR
The receptor for the urokinase-type plasminogen activator (uPAR) is a widely recognized
master regulator of cell migration, and uPAR88–92 is the minimal sequence required to …
master regulator of cell migration, and uPAR88–92 is the minimal sequence required to …
The blocking of uPAR suppresses lipopolysaccharide‐induced inflammatory osteoclastogenesis and the resultant bone loss through attenuation of integrin β3/Akt …
Y Kanno, A Ishisaki, M Miyashita… - Immunity, inflammation …, 2016 - Wiley Online Library
Introduction Chronic inflammatory diseases, such as rheumatoid arthritis and periodontitis,
cause the bone destruction by promotion of the differentiation of monocyte/macrophage …
cause the bone destruction by promotion of the differentiation of monocyte/macrophage …
[HTML][HTML] Transcriptomic pathway analysis of urokinase receptor silenced breast cancer cells: a microarray study
PB Narayanaswamy, TK Baral, H Haller, I Dumler… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Urokinase plasminogen activator receptor (PLAUR) has been implicated in a variety of
physiological and pathological conditions. The multi-functionality of PLAUR is due to its …
physiological and pathological conditions. The multi-functionality of PLAUR is due to its …
The roles of urokinase-type plasminogen activator in leukocyte infiltration and inflammatory responses in mice corneas treated with lipopolysaccharide
K Sugioka, A Kodama, K Yoshida… - … & Visual Science, 2014 - iovs.arvojournals.org
Purpose.: Urokinase-type plasminogen activator (u-PA) plays an important role in corneal
wound healing, yet its role in corneal inflammation remains poorly understood. We …
wound healing, yet its role in corneal inflammation remains poorly understood. We …
Gingival crevicular fluid zinc-and aspartyl-binding protease profile of individuals with moderate/severe atopic dermatitis
F Valenzuela, J Fernández, M Aroca, C Jiménez… - Biomolecules, 2020 - mdpi.com
Atopic dermatitis (AD) is a protease-modulated chronic disorder with heterogenous clinical
manifestations which may lead to an imprecise diagnosis. To date, there are no diagnostic …
manifestations which may lead to an imprecise diagnosis. To date, there are no diagnostic …
[HTML][HTML] Involvement of urokinase in cigarette smoke extract-induced epithelial–mesenchymal transition in human small airway epithelial cells
Q Wang, Y Wang, Y Zhang, Y Zhang, W Xiao - Laboratory Investigation, 2015 - Elsevier
Urokinase-type plasminogen activator (uPA) augments inflammation and tissue remodeling
during lung injury and repair. The uPA expression in small airway epithelium of chronic …
during lung injury and repair. The uPA expression in small airway epithelium of chronic …
Moesin and merlin regulate urokinase receptor-dependent endothelial cell migration, adhesion and angiogenesis
B Degryse, M Britto, CX Shan, RG Wallace… - … International Journal of …, 2017 - Elsevier
The glycosyl-phosphatidyl-inositol (GPI)-anchored urokinase receptor (uPAR) has no
intracellular domain, but nevertheless initiates signalling through proximal interactions with …
intracellular domain, but nevertheless initiates signalling through proximal interactions with …