Improved CT-based estimate of pulmonary gas trapping accounting for scanner and lung-volume variations in a multicenter asthmatic study

S Choi, EA Hoffman, SE Wenzel… - Journal of Applied …, 2014 - journals.physiology.org
Lung air trapping is estimated via quantitative computed tomography (CT) using density
threshold-based measures on an expiration scan. However, the effects of scanner …

Pulmonary arterial pruning and longitudinal change in percent emphysema and lung function: the genetic epidemiology of COPD study

CL Pistenmaa, P Nardelli, SY Ash, CE Come, AA Diaz… - Chest, 2021 - Elsevier
Background Pulmonary endothelial damage has been shown to precede the development
of emphysema in animals, and vascular changes in humans have been observed in COPD …

Chronic bronchitis is associated with worse symptoms and quality of life than chronic airflow obstruction

PM Meek, H Petersen, GR Washko, AA Diaz, V Klm… - Chest, 2015 - Elsevier
BACKGROUND COPD includes the chronic bronchitis (CB) and emphysema phenotypes.
Although it is generally assumed that emphysema or chronic airflow obstruction (CAO) is …

Thoracic applications of dual-source CT technology

K Boroto, M Remy-Jardin, T Flohr, JB Faivre… - European journal of …, 2008 - Elsevier
Among the various imaging modalities available, CT has remained over time the core
imaging technique for the evaluation of respiratory disorders. The recent advent of dual …

Reference standard and statistical model for intersite and temporal comparisons of CT attenuation in a multicenter quantitative lung study

JP Sieren, JD Newell Jr, PF Judy, DA Lynch… - Medical …, 2012 - Wiley Online Library
Purpose: The purpose of this study was to detect and analyze anomalies between a large
number of computed tomography (CT) scanners, tracked over time, utilized to collect human …

Lung perfusion measured using magnetic resonance imaging: new tools for physiological insights into the pulmonary circulation

SR Hopkins, GK Prisk - Journal of Magnetic Resonance …, 2010 - Wiley Online Library
Since the lung receives the entire cardiac output, sophisticated imaging techniques are not
required in order to measure total organ perfusion. However, for many years studying lung …

Quantitative CT imaging and advanced visualization methods: potential application in novel coronavirus disease 2019 (COVID-19) pneumonia

P Nagpal, J Guo, KM Shin, JK Lim, KB Kim… - BJR| Open, 2021 - academic.oup.com
Increasingly, quantitative lung computed tomography (qCT)-derived metrics are providing
novel insights into chronic inflammatory lung diseases, including chronic obstructive …

Quantifying tracheobronchial tree dimensions: methods, limitations and emerging techniques

JP Williamson, AL James, MJ Phillips… - European …, 2009 - Eur Respiratory Soc
The ability to measure airway dimensions is important for clinicians, interventional
bronchoscopists and researchers in order to accurately quantify structural abnormalities and …

Ambient air pollution and pulmonary vascular volume on computed tomography: the MESA Air Pollution and Lung cohort studies

CP Aaron, EA Hoffman, SM Kawut… - European …, 2019 - Eur Respiratory Soc
Background Air pollution alters small pulmonary vessels in animal models. We hypothesised
that long-term ambient air pollution exposure would be associated with differences in …

The lung physiome: merging imaging‐based measures with predictive computational models

MH Tawhai, EA Hoffman, CL Lin - … Reviews: Systems Biology …, 2009 - Wiley Online Library
Global measurements of the lung provided by standard pulmonary function tests do not give
insight into the regional basis of lung function and lung disease. Advances in imaging …