Controlled, parametric, individualized, 2-D and 3-D imaging measurements of aerosol deposition in the respiratory tract of asthmatic human subjects for model …

J Fleming, J Conway, C Majoral, I Katz… - Journal of aerosol …, 2015 - liebertpub.com
Background: Computer modeling is used to predict inhaled aerosol deposition in the lung
based on definition of the aerosol characteristics and the breathing pattern and airway …

Dynamic pulmonary CT perfusion using first-pass analysis technique with only two volume scans: Validation in a swine model

Y Zhao, L Hubbard, S Malkasian, P Abbona, S Molloi - PLoS One, 2020 - journals.plos.org
Purpose To evaluate the accuracy of a low-dose first-pass analysis (FPA) CT pulmonary
perfusion technique in comparison to fluorescent microsphere measurement as the …

Airway bypass site selection and treatment planning

H Wibowo, EJ Roschak, T Keast, C Cole - US Patent 8,668,652, 2014 - Google Patents
US8668652B2 - Airway bypass site selection and treatment planning - Google Patents
US8668652B2 - Airway bypass site selection and treatment planning - Google Patents Airway …

Not all measures of hyperinflation are created equal: lung structure and clinical correlates of gas trapping and hyperexpansion in COPD: the Multi-Ethnic Study of …

BM Smith, EA Hoffman, RC Basner, SM Kawut… - Chest, 2014 - Elsevier
Background Hyperinflation refers to a nonspecific increase in absolute lung volumes and
has a poor prognosis in COPD. The relative contribution of increased airways resistance …

Quantitative imaging of COPD

DA Lynch, JD Newell - Journal of thoracic imaging, 2009 - journals.lww.com
Computed tomography has facilitated recognition that chronic obstructive pulmonary
disease is not a single disease but encompasses several overlapping entities, including …

Sex differences in emphysema phenotype in smokers without airflow obstruction

N Sverzellati, E Calabrò, G Randi… - European …, 2009 - Eur Respiratory Soc
Data on sex differences in emphysema are limited to chronic obstructive pulmonary disease.
We aimed to verify whether such differences also exist in smokers without airflow …

Are asthma and COPD a continuum of the same disease?

X Soler, JW Ramsdell - The Journal of Allergy and Clinical Immunology: In …, 2015 - Elsevier
Asthma and chronic obstructive pulmonary disease (COPD) are common heterogeneous
diseases with significant impact on morbidity, mortality, and health care costs. In most of the …

Variation of densitometry on computed tomography in COPD–influence of different software tools

MO Wielpütz, D Bardarova, O Weinheimer… - PloS one, 2014 - journals.plos.org
Objectives Quantitative multidetector computed tomography (MDCT) as a potential
biomarker is increasingly used for severity assessment of emphysema in chronic obstructive …

New insights on COPD imaging via CT and MRI

N Sverzellati, F Molinari, T Pirronti… - … journal of chronic …, 2007 - Taylor & Francis
Multidetector-row computed tomography (MDCT) can be used to quantify morphological
features and investigate structure/function relationship in COPD. This approach allows a …

Adaptive quantification and longitudinal analysis of pulmonary emphysema with a hidden Markov measure field model

Y Häme, ED Angelini, EA Hoffman… - IEEE transactions on …, 2014 - ieeexplore.ieee.org
The extent of pulmonary emphysema is commonly estimated from CT scans by computing
the proportional area of voxels below a predefined attenuation threshold. However, the …