Rationale and Objectives: Asthma is associated with chronic airflow obstruction. Our goal
was to assess the association of computed tomographic measures of airway wall volume …

Rationale and Objectives: Density-based metrics assess severity of lung disease but vary
with lung inflation and method of scanning. The aim of this study was to evaluate the …

Abstract Background Chronic Obstructive Pulmonary Disease (COPD) is among the leading
causes of death worldwide. Inhaled pollutants are the prime risk factor, but the pathogenesis …

Abstract Background Multi-detector Computed Tomography has become an invaluable tool
for the diagnosis of chronic respiratory diseases. Based on CT images, the automatic …

BACKGROUND: The potential consequences of asthma in childhood and young adulthood
on lung structure in older adults have not been studied in a large, population-based cohort …

Airway remodeling is an important pathophysiological mechanism in a variety of chronic
airway diseases. Historically investigators have had to use invasive techniques such as …

Abstract The fucosyltransferase 8 gene (FUT8) encodes an enzyme that transfers fucose to
the innermost N-acetylglucosamine unit of N-glycan chains. Recent study showed that fut8 …

Rationale: Air trapping and ventilation defects on imaging are characteristics of asthma.
Airway wall thickening occurs in asthma and is associated with increased bronchial …

Indices of Childhood Socioeconomic Status and Dysanapsis among Older Adults: The Multi-Ethnic
Study of Atherosclerosis Lung Stud Page 1 Indices of Childhood Socioeconomic Status and …

Rationale Given that the diagnosis of chronic obstructive pulmonary disease (COPD) relies
on demonstrating airflow limitation by spirometry, which is known to be poorly sensitive to …