Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research
DS Quintana, A Lischke, S Grace, D Scheele… - Molecular …, 2021 - nature.com
Reports on the modulatory role of the neuropeptide oxytocin on social cognition and
behavior have steadily increased over the last two decades, stimulating considerable …
behavior have steadily increased over the last two decades, stimulating considerable …
Progress in brain targeting drug delivery system by nasal route
AR Khan, M Liu, MW Khan, G Zhai - Journal of Controlled Release, 2017 - Elsevier
The blood–brain barrier (BBB) restricts the transport of potential therapeutic moieties to the
brain. Direct targeting the brain via olfactory and trigeminal neural pathways by passing the …
brain. Direct targeting the brain via olfactory and trigeminal neural pathways by passing the …
[HTML][HTML] Recent advances in carrier mediated nose-to-brain delivery of pharmaceutics
V Bourganis, O Kammona, A Alexopoulos… - European Journal of …, 2018 - Elsevier
Central nervous system (CNS) disorders (eg, multiple sclerosis, Alzheimer's disease, etc.)
represent a growing public health issue, primarily due to the increased life expectancy and …
represent a growing public health issue, primarily due to the increased life expectancy and …
Nanoemulsions for “nose-to-brain” drug delivery
The blood–brain barrier (BBB) plays a fundamental role in protecting the brain from toxic
substances and therefore also controls and restricts the entry of therapeutic agents. The …
substances and therefore also controls and restricts the entry of therapeutic agents. The …
An allostatic theory of oxytocin
DS Quintana, AJ Guastella - Trends in cognitive sciences, 2020 - cell.com
Oxytocin has garnered considerable interest for its role in social behavior, as well as for the
potential of intranasal administration to treat social difficulties. However, current theoretical …
potential of intranasal administration to treat social difficulties. However, current theoretical …
The correlation between central and peripheral oxytocin concentrations: a systematic review and meta-analysis
M Valstad, GA Alvares, M Egknud… - Neuroscience & …, 2017 - Elsevier
There is growing interest in the role of the oxytocin system in social cognition and behavior.
Peripheral oxytocin concentrations are regularly used to approximate central concentrations …
Peripheral oxytocin concentrations are regularly used to approximate central concentrations …
Kinetics and dose dependency of intranasal oxytocin effects on amygdala reactivity
Background Current neuroimaging perspectives on a variety of mental disorders emphasize
dysfunction of the amygdala. The neuropeptide oxytocin (OXT), a key mediator in the …
dysfunction of the amygdala. The neuropeptide oxytocin (OXT), a key mediator in the …
Effect of intranasal oxytocin on the core social symptoms of autism spectrum disorder: a randomized clinical trial
Although small-scale studies have described the effects of oxytocin on social deficits in
autism spectrum disorder (ASD), no large-scale study has been conducted. In this …
autism spectrum disorder (ASD), no large-scale study has been conducted. In this …
Design and application in delivery system of intranasal antidepressants
J Xu, J Tao, J Wang - Frontiers in Bioengineering and Biotechnology, 2020 - frontiersin.org
One of the major reasons why depressed patients fail their treatment course is the existence
of the blood-brain barrier (BBB), which prevents drugs from being delivered to the central …
of the blood-brain barrier (BBB), which prevents drugs from being delivered to the central …
Oxytocin—a social peptide? Deconstructing the evidence
In this paper, we analyse the claim that oxytocin is a 'social neuropeptide'. This claim
originated from evidence that oxytocin was instrumental in the initiation of maternal …
originated from evidence that oxytocin was instrumental in the initiation of maternal …