Bordetella respiratory infections are common in people (B. pertussis) and in animals (B.
bronchiseptica). During the last two decades, much has been learned about the virulence …

In most countries, pertussis surveillance is inadequate for accurately estimating numbers of
cases or deaths. Good estimates are needed to help set priorities for vaccination …

An analysis assessing for associations between pertactin production and both clinical
presentation and vaccine history found a significant association between vaccination and …

In a pertussis vaccine efficacy trial in Germany we collected sera from vaccinees (DTaP or
DTP) after the third and fourth doses of vaccine or at comparable time periods in DT vaccine …

In the past decade, numerous sources have noted an increase in reported pertussis in
highly immunized populations. This has been accompanied by a perceived change in …

Many emerging and reemerging bacterial pathogens synthesize toxins that serve as primary
virulence factors. We highlight seven bacterial toxins produced by well-established or newly …

Background. Despite widespread vaccination during 30 years, the hypothesis of a
resurgence of pertussis in France has been raised by outbreaks and sporadic case reports …

The adhesin pertactin (Prn) is one of the major virulence factors of Bordetella pertussis, the
etiological agent of whooping cough. However, a significant prevalence of Prn-deficient …

Pertussis is a highly contagious acute respiratory illness classically known as “whooping
cough” because of its characteristic cough. The majority of cases are caused by Bordetella …

Many countries continue to experience pertussis epidemics despite widespread vaccination.
Waning protection after booster vaccination has highlighted the need for a better …