The 90-kDa molecular chaperone family (which comprises, among other proteins, the 90-
kDa heat-shock protein, hsp90 and the 94-kDa glucose-regulated protein, grp94, major …

Heat shock proteins (Hsp) form the most ancient defense system in all living organisms on
earth. These proteins act as molecular chaperones by helping in the refolding of misfolded …

Great expectations from the application of gene therapy approaches to human disease have
been impaired by the unsatisfactory clinical progress observed. Among others, the use of an …

The chicken anemia virus protein apoptin induces a p53-independent, Bcl-2-insensitive type
of apoptosis in various human tumor cells. Here, we show that, in vitro, apoptin fails to …

Chaperones/heat shock proteins (HSPs) of the HSP90 and HSP70 families show elevated
levels in proliferating mammalian cells and a cell cycle‐dependent expression. They …

Regucalcin was discovered in 1978 as a Ca2+-binding protein that does not contain EF-
hand motif of Ca2+-binding domain. The name regucalcin was proposed for this Ca22+ …

The heat shock proteins (hsp) are ubiquitous molecules induced in cells exposed to
sublethal heat shock, present in all living cells, and highly conserved during evolution. Their …

The process of nuclear protein transport requires the interaction of several different proteins,
either directly or indirectly with nuclear localization or targeting sequences (NLS). Recently …

Regucalcin was discovered in 1978 as a calcium-binding protein that does not contain EF-
hand motif of Ca2+-binding domain [M. Yamaguchi and T. Yamamoto, Chem. Pharm. Bull …

The microtubule-binding integral 63 kD cytoskeleton-linking membrane protein (CLIMP-63;
former name, p63) of the rough endoplasmic reticulum (ER) is excluded from the nuclear …