Pathogenesis of viral infections during pregnancy

PS Creisher, SL Klein - Clinical Microbiology Reviews, 2024 - Am Soc Microbiol
Viral infections during pregnancy are associated with significant adverse perinatal and fetal
outcomes. Pregnancy is a unique immunologic and physiologic state, which can influence …

Antiretroviral therapy in pregnancy: a 2023 review of the literature

AN Goulding, K Meeks, L Shay, S Casey… - Current HIV/AIDS …, 2024 - Springer
Abstract Purpose of Review Selection of antiretroviral therapy during pregnancy must
consider maternal physiology and resulting pharmacokinetic changes in pregnancy …

Suppression of progesterone by influenza A virus mediates adverse maternal and fetal outcomes in mice

PS Creisher, MA Parish, J Lei, J Liu, JL Perry… - Mbio, 2024 - Am Soc Microbiol
Influenza A virus infection during pregnancy can cause adverse maternal and fetal
outcomes but the mechanism responsible remains elusive. Infection of outbred mice with …

Weight Changes and Adverse Pregnancy Outcomes With Dolutegravir-and Tenofovir Alafenamide Fumarate–Containing Antiretroviral Treatment Regimens During …

RM Hoffman, S Brummel, L Ziemba… - Clinical Infectious …, 2024 - academic.oup.com
Background We evaluated associations between antepartum weight change and adverse
pregnancy outcomes and between antiretroviral therapy (ART) regimens and week 50 …

[PDF][PDF] Pathology of HIV/AIDS

EC Klatt - The Mercer University of Medicine Savannah, 2017 - webpath.med.utah.edu
The human immunodeficiency virus (HIV) was unknown until the early 1980's when
increasing numbers of cases of unusual opportunistic infections and Kaposi sarcoma in …

Challenges, risks, and opportunities of antiretroviral drugs in women of reproductive potential

AC Henderson, P Cholli, MA Lampe… - Expert Review of Anti …, 2024 - Taylor & Francis
ABSTRACT Introduction The HIV/AIDS epidemic has been one of the greatest challenges in
global health, significantly affecting women of reproductive potential. Considerable …

Maintenance darunavir/ritonavir monotherapy to prevent perinatal HIV transmission, ANRS-MIE 168 MONOGEST study

L Mandelbrot, R Tubiana, P Frange… - Journal of …, 2023 - academic.oup.com
Abstract Objectives Because NRTIs can have fetal toxicities, we evaluated a perinatal NRTI-
sparing strategy to prevent perinatal HIV transmission. Our primary objective was to …

[HTML][HTML] Pediatric immunotherapy and HIV control

TT Chinunga, A Chahroudi… - Current Opinion in HIV …, 2024 - journals.lww.com
Understanding early events during HIV infection and disease progression in CLWH serves
as a foundation for predicting or targeting later outcomes by harnessing the immune …

Pharmacokinetic and toxicological considerations affecting antiretroviral drug dosing in pregnant women

Z Todorović, G Dragović, R Lukić - Expert Opinion on Drug …, 2024 - Taylor & Francis
Introduction To prevent mother-to-child transmission (PMTCT) of the human
immunodeficiency virus (HIV) during pregnancy, the appropriate dosing regimens of …

Impact of maternal HIV infection on perinatal outcomes: A systematic review

I Atowoju, P Dawer, M Asrani… - International Journal of …, 2024 - Wiley Online Library
Background Maternal HIV infection remains a significant global health concern with potential
repercussions on perinatal outcomes. Emphasis on early intervention to improve peri‐and …