ctDNA as a cancer biomarker: A broad overview

LS Pessoa, M Heringer, VP Ferrer - Critical reviews in oncology …, 2020 - Elsevier
Circulating tumor DNA (ctDNA) in fluids has gained attention because ctDNA seems to
identify tumor-specific abnormalities, which could be used for diagnosis, follow-up of …

The role of extracellular vesicles in the hallmarks of cancer and drug resistance

CPR Xavier, HR Caires, MAG Barbosa, R Bergantim… - Cells, 2020 - mdpi.com
Extracellular vesicles (EVs) mediate intercellular signaling and communication, allowing the
intercellular exchange of proteins, lipids, and genetic material. Their recognized role in the …

[PDF][PDF] The global burden of pancreatic cancer

G Lippi, C Mattiuzzi - Archives of Medical Science, 2020 - termedia.pl
Results Overall, 447 665 new cases of pancreatic cancer were recorded around the world in
2017 (58.6 per million), with global prevalence of 49.8 per million and 441 083 deaths (57.7 …

Tumor-derived extracellular vesicles inhibit natural killer cell function in pancreatic cancer

J Zhao, HA Schlößer, Z Wang, J Qin, J Li, F Popp… - Cancers, 2019 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies. Tumor-
derived extracellular vesicles (EVs) induce pre-metastatic niche formation to promote …

Circulating extracellular vesicle‐encapsulated HULC is a potential biomarker for human pancreatic cancer

K Takahashi, Y Ota, T Kogure, Y Suzuki… - Cancer …, 2020 - Wiley Online Library
The role of long noncoding RNAs (lncRNAs) in the epithelial‐mesenchymal transition (EMT)
in pancreatic ductal adenocarcinoma (PDAC) is unclear. Some lncRNAs can be transferred …

Latest advances in extracellular vesicles: from bench to bedside

T Yamamoto, N Kosaka, T Ochiya - Science and Technology of …, 2019 - Taylor & Francis
Extracellular vesicles (EVs) are small membraned vesicles and approximately 50–150 nm in
diameter. Almost all of the type of cells releases the EVs and circulates in the body fluids …

When tissue is an issue the liquid biopsy is nonissue: a review

J Rodríguez, J Avila, C Rolfo, A Ruíz-Patiño… - Oncology and …, 2021 - Springer
Precision medicine has impacted the field of medical oncology by introducing personalized
therapies, improving all measurable outcomes. This field, in turn, has expanded to obtaining …

Liquid biopsy in pancreatic cancer: Are we ready to apply it in the clinical practice?

V Heredia-Soto, N Rodríguez-Salas, J Feliu - Cancers, 2021 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is one of the tumors with the
highest mortality, for which survival has hardly changed in the last 40 years. This high …

Current status of circulating tumor DNA liquid biopsy in pancreatic cancer

MW Grunvald, RA Jacobson, TM Kuzel… - International Journal of …, 2020 - mdpi.com
Pancreatic cancer is a challenging disease with a low 5-year survival rate. There are areas
for improvement in the tools used for screening, diagnosis, prognosis, treatment selection …

The translational status of cancer liquid biopsies

S Bratulic, F Gatto, J Nielsen - Regenerative Engineering and …, 2021 - Springer
Precision oncology aims to tailor clinical decisions specifically to patients with the objective
of improving treatment outcomes. This can be achieved by leveraging omics information for …