[HTML][HTML] Hippo signaling pathway and respiratory diseases

W Tang, M Li, X Yangzhong, X Zhang, A Zu… - Cell Death …, 2022 - nature.com
The hippo signaling pathway is a highly conserved evolutionary signaling pathway that
plays an important role in regulating cell proliferation, organ size, tissue development, and …

The impact of ACE and ACE2 gene polymorphisms in pulmonary diseases including COVID-19

I Gintoni, M Adamopoulou, C Yapijakis - in vivo, 2022 - iv.iiarjournals.org
Chronic and acute respiratory diseases pose a major problem for public health worldwide
due to the high morbidity and mortality rates, while treatment options remain mostly …

[HTML][HTML] Ficolin B secreted by alveolar macrophage exosomes exacerbates bleomycin-induced lung injury via ferroptosis through the cGAS-STING signaling pathway

X Wu, Y Jiang, R Li, Y Xia, F Li, M Zhao, G Li… - Cell Death & …, 2023 - nature.com
Pathogenesis exploration and timely intervention of lung injury is quite necessary as it has
harmed human health worldwide for years. Ficolin B (Fcn B) is a recognition molecule that …

Sophflarine A, a novel matrine-derived alkaloid from Sophora flavescens with therapeutic potential for non-small cell lung cancer through ROS-mediated pyroptosis …

D Luo, X Dai, H Tian, C Fan, H Xie, N Chen, J Wang… - Phytomedicine, 2023 - Elsevier
Background Novel compounds and more efficient treatment options are urgently needed for
the treatment of non-small cell lung cancer (NSCLC). The decoction of Sophora flavescens …

[HTML][HTML] Focus on long non-coding RNA MALAT1: Insights into acute and chronic lung diseases

X Lai, J Zhong, A Zhang, B Zhang, T Zhu… - Frontiers in Genetics, 2022 - frontiersin.org
Acute lung injury (ALI) is a pulmonary illness with a high burden of morbidity and mortality
around the world. Chronic lung diseases also represent life-threatening situations …

[HTML][HTML] The inhibitory effect of quercetin-3-glucuronide on pulmonary injury in vitro and in vivo

PR Yu, JY Hsu, CY Tseng, JH Chen… - Journal of Food and Drug …, 2023 - ncbi.nlm.nih.gov
Pulmonary injury is defined as a progressive inflammation. Extensive pro-inflammatory
cytokines are secreted from alveolus, associated with the production of reactive oxygen …

[HTML][HTML] Administration of protopine prevents mitophagy and acute lung injury in sepsis

Z Xiao, J Long, J Zhang, Z Qiu, C Zhang… - Frontiers in …, 2023 - frontiersin.org
Introduction: Sepsis is a severe life-threatening infection that induces a series of
dysregulated physiologic responses and results in organ dysfunction. Acute lung injury …

[HTML][HTML] Necroptosis in pulmonary diseases: a new therapeutic target

L Wang, L Zhou, Y Zhou, L Liu, W Jiang… - Frontiers in …, 2021 - frontiersin.org
In the past decades, apoptosis has been the most well-studied regulated cell death (RCD)
that has essential functions in tissue homeostasis throughout life. However, a novel form of …

Irisin ameliorates pm2. 5-induced acute lung injury by regulation of autophagy through AMPK/mTOR pathway

J Ma, Z Han, R Jiao, G Yuan, C Ma, X Yan… - Journal of …, 2023 - Taylor & Francis
Background PM2. 5 exposure is one of the major inducements of various respiratory
diseases and related mortality. Meanwhile, irisin, a metabolism and thermogenesis-related …

Liensinine ameliorates ischemia–reperfusion-induced brain injury by inhibiting autophagy via PI3K/AKT signaling

W Qiao, Z Zang, D Li, S Shao, Q Li, Z Liu - Functional & Integrative …, 2023 - Springer
The current study aimed to explore the role of autophagy in cerebral ischemia–reperfusion
injuries (CIRI) and elucidate the efficacy of liensinine treatment. An in vitro ischemia …