Recent applications of immunomodulatory biomaterials for disease immunotherapy
Immunotherapy is used to regulate systemic hyperactivation or hypoactivation to treat
various diseases. Biomaterial‐based immunotherapy systems can improve therapeutic …
various diseases. Biomaterial‐based immunotherapy systems can improve therapeutic …
Advances in extracellular vesicle nanotechnology for precision theranostics
Q Wu, S Fu, H Xiao, J Du, F Cheng, S Wan… - Advanced …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) have increasingly been recognized as important cell surrogates
influencing many pathophysiological processes, including cellular homeostasis, cancer …
influencing many pathophysiological processes, including cellular homeostasis, cancer …
Engineered extracellular vesicles with SHP2 high expression promote mitophagy for Alzheimer's disease treatment
Mitochondrial dysfunction is a fundamental pathological feature of Alzheimer's disease (AD).
However, toxicity and poor brain enrichment of existing mitophagy inducers limit their further …
However, toxicity and poor brain enrichment of existing mitophagy inducers limit their further …
[HTML][HTML] Oral feeding of nanoplastics affects brain function of mice by inducing macrophage IL-1 signal in the intestine
Nanoplastics (NPs) as contaminants in food and water have drawn increasing public
attention. However, little is known about how NPs shape the gut immune landscape after …
attention. However, little is known about how NPs shape the gut immune landscape after …
Vesicular antibodies: shedding light on antibody therapeutics with cell membrane nanotechnology
The high stability of antibodies and their ability to precisely bind to antigens and
endogenous immune receptors, as well as their susceptibility to protein engineering, enable …
endogenous immune receptors, as well as their susceptibility to protein engineering, enable …
[HTML][HTML] Engineered mesenchymal stem cell-derived extracellular vesicles: a state-of-the-art multifunctional weapon against Alzheimer's disease
T Yin, Y Liu, W Ji, J Zhuang, X Chen, B Gong, J Chu… - Theranostics, 2023 - ncbi.nlm.nih.gov
With the increase of population aging, the number of Alzheimer's disease (AD) patients is
also increasing. According to current estimates, approximately 11% of people over 65 suffer …
also increasing. According to current estimates, approximately 11% of people over 65 suffer …
A Curcumin‐Modified Coordination Polymers with ROS Scavenging and Macrophage Phenotype Regulating Properties for Efficient Ulcerative Colitis Treatment
H Yao, F Wang, H Chong, J Wang, Y Bai… - Advanced …, 2023 - Wiley Online Library
Overexpression of classically activated macrophages (M1) subtypes and assessed reactive
oxygen species (ROS) levels are often observed in patients with ulcerative colitis. At present …
oxygen species (ROS) levels are often observed in patients with ulcerative colitis. At present …
Signaling pathways and targeted therapies for psoriasis
J Guo, H Zhang, W Lin, L Lu, J Su… - Signal Transduction and …, 2023 - nature.com
Psoriasis is a common, chronic, and inflammatory skin disease with a high burden on
individuals, health systems, and society worldwide. With the immunological pathologies and …
individuals, health systems, and society worldwide. With the immunological pathologies and …
MicroRNAs in extracellular vesicles: sorting mechanisms, diagnostic value, isolation, and detection technology
D Xu, K Di, B Fan, J Wu, X Gu, Y Sun… - … in Bioengineering and …, 2022 - frontiersin.org
MicroRNAs (miRNAs) are a class of short, single-stranded, noncoding RNAs, with a length
of about 18–22 nucleotides. Extracellular vesicles (EVs) are derived from cells and play a …
of about 18–22 nucleotides. Extracellular vesicles (EVs) are derived from cells and play a …
Mechanoelectronic stimulation of autologous extracellular vesicle biosynthesis implant for gut microbiota modulation
S Wan, K Wang, P Huang, X Guo, W Liu, Y Li… - Nature …, 2024 - nature.com
Pathogenic gut microbiota is responsible for a few debilitating gastrointestinal diseases.
While the host immune cells do produce extracellular vesicles to counteract some …
While the host immune cells do produce extracellular vesicles to counteract some …