Novel ligand platforms that promote reactivity are of long standing and continued interest in
coordination chemistry, with Schiff base ligands and their metal complexes representing one …

The use of radionuclides in medicine is based largely on the discoveries of two critical
concepts, the “tracer principle” and the “magic bullet”. In 1913, George de Hevesy …

There has been fast-growing interest in the exploitation of the photophysical and
photochemical properties of luminescent transition metal complexes in biological …

The objective of medical imaging using molecular probes and perfusion radiotracers is to
provide rapid, noninvasive evaluation of physiology, pathology, and/or organ function. The …

Cyclams are 14-membered tetraamine macrocycles which bind strongly to a wide range of
metal ions. Medical interest has centred on clinical trials of a bicyclam for the treatment of …

A review on the synthesis and properties of the organometallic aqua-ion [M (OH2) 3 (CO)
3]+(M= Re, 99Tc, 99mTc), as relevant for radiopharmaceutical application, is presented …

Publisher Summary Biomedical inorganic chemistry “Elemental Medicine” is an important
new area of chemistry. Platinum complexes are now among the most widely used drugs for …

The progress in diagnostic nuclear medicine over the years since the discovery of 99mTc is
indeed phenomenal. Over 80% of the radiopharmaceuticals currently being used make use …

An updated, practical guide to bioinorganic chemistry Bioinorganic Chemistry: A Short
Course, Second Edition provides the fundamentals of inorganic chemistry and biochemistry …

This review summarizes some of the developments of metal complexes and metal-complex-
bioconjugates for the diagnosis of disease states that have occurred over the past 10 years …