In patients with heart failure (HF), the neuroendocrine systems of the sympathetic nervous
system (SNS), the renin–angiotensin–aldosterone system (RAAS) and the arginine …

Aims This study aimed to investigate the impact of cardiac resynchronization therapy with a
defibrillator (CRT-D) on mortality, comparing it with CRT with a pacemaker (CRT-P) …

Abstract Aims The HeartLogic Index combines data from multiple implantable cardioverter
defibrillators (ICDs) sensors and has been shown to accurately stratify patients at risk of …

Current guidelines lack clear recommendations between the implantation of cardiac
resynchronization therapy (CRT) with defibrillator (CRT-D) and CRT with pacemaker (CRT …

Background: Cardiac resynchronization therapy (CRT) has evolved into an established
therapy for patients with chronic heart failure and a wide QRS complex. Data on long-term …

Since 2000s CRT became a revolutionary therapy for heart failure with reduced left
ventricular ejection fraction (HFrEF) and wide QRS. However, about one third of CRT …

Aims Data on repolarization parameters in cardiac resynchronization therapy (CRT) are
scarce. We investigated the association of baseline T-wave area, with both clinical and …

Background The utility of atrioventricular (AV) optimization (AVO) algorithms remains in
question. A substudy of the SMART-AV trial found that patients with prolonged …

Aims We aimed to investigate the influence of socioeconomic position (SEP) and
multimorbidity on cross-sectional healthcare utilization and prognosis in patients after …

Aims The trials upon which recommendations for the use of cardiac resynchronization
therapy (CRT) in heart failure used optimal medical therapy (OMT) before sodium‐glucose …