Chagas' disease

C Bern - New England Journal of Medicine, 2015 - Mass Medical Soc
Chagas’ Disease | New England Journal of Medicine Skip to main content The New England
Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology Clinical …

[HTML][HTML] Experimental and clinical treatment of Chagas disease: a review

PAS Junior, I Molina, SMF Murta… - The American journal …, 2017 - ncbi.nlm.nih.gov
Chagas disease (CD) is caused by the protozoan parasite Trypanosoma cruzi that infects a
broad range of triatomines and mammalian species, including man. It afflicts 8 million …

Identification of vaccine targets in pathogens and design of a vaccine using computational approaches

K Rawal, R Sinha, BA Abbasi, A Chaudhary, SK Nath… - Scientific reports, 2021 - nature.com
Antigen identification is an important step in the vaccine development process.
Computational approaches including deep learning systems can play an important role in …

Chagas disease: an overview of clinical and epidemiological aspects

MCP Nunes, W Dones, CA Morillo, JJ Encina… - Journal of the American …, 2013 - jacc.org
Chagas disease, caused by the parasite Trypanosoma cruzi, is a serious health problem in
Latin America and is an emerging disease in non-endemic countries. In recent decades, the …

Nitro drugs for the treatment of trypanosomatid diseases: past, present, and future prospects

S Patterson, S Wyllie - Trends in parasitology, 2014 - cell.com
There is an urgent need for new, safer, and effective treatments for the diseases caused by
the protozoan parasites Trypanosoma brucei, Trypanosoma cruzi, and Leishmania spp. In …

Chagas disease drug discovery: toward a new era

E Chatelain - Journal of biomolecular screening, 2015 - journals.sagepub.com
American trypanosomiasis, or Chagas disease, is the result of infection by the Trypanosoma
cruzi parasite. Endemic in Latin America where it is the major cause of death from …

Diagnosis and management of Chagas disease and cardiomyopathy

AL Ribeiro, MP Nunes, MM Teixeira… - Nature Reviews …, 2012 - nature.com
Chagas cardiomyopathy is the most severe and life-threatening manifestation of human
Chagas disease—a'neglected'tropical disease caused by the protozoan parasite …

[PDF][PDF] The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases-part II

TJ Schmidt, SA Khalid, AJ Romanha, TMA Alves… - 2012 - lavierebelle.org
Infections with protozoan parasites are a major cause of disease and mortality in many
tropical countries of the world. Diseases caused by species of the genera Trypanosoma …

Between a bug and a hard place: Trypanosoma cruzi genetic diversity and the clinical outcomes of Chagas disease

LA Messenger, MA Miles, C Bern - Expert review of anti-infective …, 2015 - Taylor & Francis
Over the last 30 years, concomitant with successful transnational disease control programs
across Latin America, Chagas disease has expanded from a neglected, endemic parasitic …

Antitrypanosomal therapy for chronic Chagas' disease

C Bern - New England Journal of Medicine, 2011 - Mass Medical Soc
Antitrypanosomal Therapy for Chronic Chagas' Disease | New England Journal of Medicine Skip
to main content The New England Journal of Medicine homepage Advanced Search SEARCH …