Interferons are multifunctional cytokines not expressed in the skin under normal
physiological conditions. However, they are overexpressed in serum and skin lesions of …

Patients with systemic lupus erythematosus (SLE) frequently suffer from nervous system
complications, termed neuropsychiatric lupus erythematosus (NPLE). NPLE accounts for the …

Background Interferon α (IFNα) is a cytokine whose production is increased endogenously
in response to viral infection and in autoimmune diseases such as systemic lupus …

Background Neuropsychiatric systemic lupus erythematosus (NPSLE) is a severe
complication, which involves pathological damage to the brain and cognitive function …

Alzheimer's disease is a devastating neurodegenerative disorder, with no disease-modifying
treatment available yet. There is increasing evidence that neuroinflammation plays a critical …

Neuropsychiatric systemic lupus erythematosus (NPSLE) is an incurable disease
characterised by neuropsychiatric symptoms, particularly depression. Novel therapeutic …

Objective Systemic lupus erythematosus (SLE) is a systemic autoimmune disease
characterized by multiorgan dysfunction. Neuropsychiatric SLE (NPSLE) occurs in 30–40 …

Objectives The central nervous system disorder in systemic lupus erythematosus (SLE),
called neuropsychiatric lupus (NPSLE), is one of the most severe phenotypes with various …

Progressive fibrosing interstitial lung diseases (PF-ILDs) result in high mortality and lack
effective therapies. The pathogenesis of PF-ILDs involves macrophages driving …

Neuropsychiatric systemic lupus erythematosus (NPSLE) is the most serious and
complicated clinical manifestation of lupus erythematosus. Cognitive dysfunction is the most …