Cancer causes considerable morbidity and mortality across the world. Socioeconomic,
environmental, and lifestyle factors contribute to the increasing cancer prevalence …

Two risk factors for the development and progression of cancers that are amenable to life
style modification are chronic inflammation and the metabolic syndrome. This review …

Objective In addition to the controversy regarding the association of hyperuricemia with
cardiovascular disease (CVD) mortality, few studies have examined the impact of a low uric …

Objectives To assess the independent and joint associations of major chronic diseases and
disease markers with cancer risk and to explore the benefit of physical activity in reducing …

Objective. To assess the associations between serum uric acid (SUA) level and mortality.
Methods. The study included 354 110 subjects without a history of gout and whose SUA …

Human xanthine oxidoreductase (XOR) catalyzes the last two steps of purine catabolism
and is present in two interconvertible forms, which may utilize O2 or NAD+ as electron …

Tumor-induced host wasting and mortality are general phenomena across species. Many
groups have previously demonstrated endocrinal impacts of malignant tumors on host …

High uric acid (UA) levels can cause gout, urolithiasis and acute and chronic nephropathy,
all of which are due to the deposit of urate crystals. There is also increasing evidence of …

Background Unlike linear models which are traditionally used to study all-cause mortality,
complex machine learning models can capture non-linear interrelations and provide …

SUA is a potent antioxidant and thus may play a protective role against cancer. Many
epidemiological studies have investigated this hypothesis but provided inconsistent and …