[HTML][HTML] Long noncoding RNA GAS5 in breast cancer: epigenetic mechanisms and biological functions

EA Filippova, MV Fridman, AM Burdennyy… - International journal of …, 2021 - mdpi.com
Long noncoding RNAs (lncRNAs) have been identified as contributors to the development
and progression of cancer through various functions and mechanisms. LncRNA GAS5 is …

New therapy strategies in the management of breast cancer

S Yardim-Akaydin, B Karahalil, SN Baytas - Drug discovery today, 2022 - Elsevier
Breast cancer (BC), the second leading cause of cancer-related deaths after lung cancer, is
the most common cancer type among women worldwide. BC comprises multiple subtypes …

[HTML][HTML] Differential non-coding RNAs expression profiles of invasive and non-invasive pituitary adenomas

O Beylerli, D Khasanov, I Gareev, E Valitov… - Non-coding RNA …, 2021 - Elsevier
Background Pituitary adenoma (PA) accounts for 10–15% of all intracranial neoplasms.
Despite their benign nature, PA often shows invasive growth. MicroRNAs (miRNAs) and …

[HTML][HTML] Long non-coding RNAs as emerging targets in lung cancer

J Gencel-Augusto, W Wu, TG Bivona - Cancers, 2023 - mdpi.com
Simple Summary Long non-coding RNAs (LncRNAs) are non-protein coding molecules
longer than 200 nucleotides. They play essential roles in normal cell function and …

Recent advances in the regulation of ABCA1 and ABCG1 by lncRNAs

S Zhang, L Li, J Wang, T Zhang, T Ye, S Wang… - Clinica Chimica …, 2021 - Elsevier
Coronary heart disease (CHD) with atherosclerosis is the leading cause of death worldwide.
ABCA1 and ABCG1 promote cholesterol efflux to suppress foam cell generation and reduce …

[HTML][HTML] Regulation of long non-coding RNAs by plant secondary metabolites: a novel anticancer therapeutic approach

MR Kalhori, H Khodayari, S Khodayari, M Vesovic… - Cancers, 2021 - mdpi.com
Simple Summary Cancer is caused by the rapid and uncontrolled growth of cells that
eventually lead to tumor formation. Genetic and epigenetic alterations are among the most …

LncRNA GAS5 regulates the Wnt/β-catenin pathway through the miR-18a-5p/AXIN2/GSK3β axis to inhibit the proliferation and migration of bladder cancer cells

Z Zhang, T Liu, C Cheng, J Wang, C Wang… - …, 2022 - academic.oup.com
LncRNA growth arrest specific 5 (GAS5) has been confirmed to play an essential role in a
number of biological processes, such as tumor regulation and gene transcription. GAS5 has …

Exploring ncRNA-mediated pathways in sepsis-induced pyroptosis

AA Bhat, Y Riadi, M Afzal, P Bansal, H Kaur… - … -Research and Practice, 2024 - Elsevier
Sepsis, a potentially fatal illness caused by an improper host response to infection, remains
a serious problem in the world of healthcare. In recent years, the role of ncRNA has …

[HTML][HTML] LncRNA GAS5 modulates the progression of non-small cell lung cancer through repressing miR-221-3p and up-regulating IRF2

J Ma, H Miao, H Zhang, J Ren, S Qu, J Da, F Xu… - Diagnostic …, 2021 - Springer
Background Long non-coding RNA growth arrest specific 5 (GAS5) is a regulator in non-
small cell lung cancer (NSCLC) progression. Nonetheless, the mechanism by which GAS5 …

[HTML][HTML] Berberine acts on C/EBPβ/lncRNA Gas5/miR-18a-5p loop to decrease the mitochondrial ROS generation in HK-2 cells

J Xu, L Liu, L Gan, Y Hu, P Xiang, Y Xing… - Frontiers in …, 2021 - frontiersin.org
Background Berberine (BBR) has therapeutic effect on diabetic nephropathy (DN), but its
molecular mechanism is not completely clear. Methods The DN model was established to …