Biological clock regulation by the PER gene family: a new perspective on tumor development

K Chen, Y Wang, D Li, R Wu, J Wang, W Wei… - Frontiers in Cell and …, 2024 - frontiersin.org
The Period (PER) gene family is one of the core components of the circadian clock, with
substantial correlations between the PER genes and cancers identified in extensive …

N-methyl-D-aspartate receptor regulates the circadian clock in megakaryocytic cells and impacts cell proliferation through BMAL1

JI Hearn, M Alhilali, M Kim, ML Kalev-Zylinska… - Platelets, 2023 - Taylor & Francis
Peripheral circadian clocks control cell proliferation and survival, but little is known about
their role and regulation in megakaryocytic cells. N-methyl-D-aspartate receptor (NMDAR) …

Effects of glyphosate exposure on the miRNA expression profile and construction of the miRNA-mRNA regulatory network in mouse bone marrow cells

J Liu, M Liu, F Xiong, K Xu, Y Pu, J Huang… - Functional & Integrative …, 2023 - Springer
Glyphosate, with the chemical name of n-phosphonomethylglycine, is an amphoteric protein
with carboxylic acid, phosphate, and amine functions. It is the main active ingredient of …

Per 基因在肿瘤中的作用机制研究进展

安平平, 范茹玉, 周施锦, 叶宣宣, 吴聪 - 中国癌症防治杂志, 2024 - zgazfz.com
昼夜节律与肿瘤的发展密切相关, 作为昼夜节律调控的核心组分, Per 基因在多种肿瘤中的表达
明显下调, 且下调程度与肿瘤的临床分期及预后密切相关. Per 基因整体被归类为抑癌基因 …

Construction of Lentiviral Vector for miR-217 Overexpression and Knockdown and Its Effect on CML

X Yang, H Jiang, C Sun - Molecular Biotechnology, 2023 - Springer
We attempted to construct a myeloid leukemia cell strain for stable overexpression and
knock-down of miR-217 and explored the possible mechanism underlying miR-217 in …