Sex and gender: modifiers of health, disease, and medicine

F Mauvais-Jarvis, NB Merz, PJ Barnes, RD Brinton… - The Lancet, 2020 - thelancet.com
Clinicians can encounter sex and gender disparities in diagnostic and therapeutic
responses. These disparities are noted in epidemiology, pathophysiology, clinical …

Higher mortality of COVID-19 in males: sex differences in immune response and cardiovascular comorbidities

LA Bienvenu, J Noonan, X Wang… - Cardiovascular …, 2020 - academic.oup.com
The high mortality rate of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
infection is a critical concern of the coronavirus disease 2019 (COVID-19) pandemic …

[HTML][HTML] Sex differences in pharmacokinetics predict adverse drug reactions in women

I Zucker, BJ Prendergast - Biology of sex differences, 2020 - Springer
Background Women experience adverse drug reactions, ADRs, nearly twice as often as
men, yet the role of sex as a biological factor in the generation of ADRs is poorly understood …

[HTML][HTML] Профилактика хронических неинфекционных заболеваний в Российской Федерации. Национальное руководство 2022

ОМ Драпкина, АВ Концевая, АМ Калинина… - Кардиоваскулярная …, 2022 - cyberleninka.ru
Члены Комитета экспертов подтвердили отсутствие финансовой поддержки/конфликта
интересов. В случае сообщения о наличии конфликта интересов, член (ы) Комитета …

[HTML][HTML] Sex matters: a comprehensive comparison of female and male hearts

SR St. Pierre, M Peirlinck, E Kuhl - Frontiers in physiology, 2022 - frontiersin.org
Cardiovascular disease in women remains under-diagnosed and under-treated. Recent
studies suggest that this is caused, at least in part, by the lack of sex-specific diagnostic …

[HTML][HTML] Gut microbiota and cardiovascular disease: opportunities and challenges

N Kazemian, M Mahmoudi, F Halperin, JC Wu… - Microbiome, 2020 - Springer
Coronary artery disease (CAD) is the most common health problem worldwide and remains
the leading cause of morbidity and mortality. Over the past decade, it has become clear that …

[HTML][HTML] Cardiac transmembrane ion channels and action potentials: cellular physiology and arrhythmogenic behavior

V András, J Tomek, N Nagy, L Virág… - Physiological …, 2021 - journals.physiology.org
Cardiac arrhythmias are among the leading causes of mortality. They often arise from
alterations in the electrophysiological properties of cardiac cells and their underlying ionic …

Estrogens in male physiology

PS Cooke, MK Nanjappa, CM Ko… - Physiological …, 2017 - journals.physiology.org
Estrogens have historically been associated with female reproduction, but work over the last
two decades established that estrogens and their main nuclear receptors (ESR1 and ESR2) …

[HTML][HTML] Gender medicine: effects of sex and gender on cardiovascular disease manifestation and outcomes

V Regitz-Zagrosek, C Gebhard - Nature Reviews Cardiology, 2023 - nature.com
Despite a growing body of evidence, the distinct contributions of biological sex and the
sociocultural dimension of gender to the manifestations and outcomes of ischaemic heart …

Time in range is associated with carotid intima-media thickness in type 2 diabetes

J Lu, X Ma, Y Shen, Q Wu, R Wang… - Diabetes technology …, 2020 - liebertpub.com
Background: Time in range (TIR) is an emerging metric of glycemic control and is reported to
be associated with microvascular complications of diabetes. We sought to investigate the …