Sex differences are widely observed under various circumstances ranging from
physiological processes to therapeutic responses, and a myriad of sex-biased genes have …

Heart failure (HF) phenotypes differ according to sex. HF preserved ejection fraction (EF)
has a greater prevalence in women and HF reduced EF (HFrEF) in men. Women with HF …

Aims Recent data from national registries suggest that acute heart failure (AHF) outcomes
might vary in men and women, however, it is not known whether this observation is …

In situ tissue engineering using bioresorbable material implants-or scaffolds-that harness
the patient's immune response while guiding neotissue formation at the site of implantation …

Sex differences in the lifetime risk and expression of disease are well-known. Preclinical
research targeted at improving treatment, increasing health span, and reducing the financial …

Aims Sex differences in cardiac fibrosis point to the regulatory role of 17β-Estradiol (E2) in
cardiac fibroblasts (CF). We, therefore, asked whether male and female CF in rodent and …

Despite the well-known sex dimorphism in cardiovascular disease traits, the exact genetic,
molecular, and cellular underpinnings of these differences are not well understood. A …

Background Increases in maximal oxygen uptake (VO 2max) are strongly associated with
improved cardiovascular health. Objective The aim was to perform a systematic review and …

NEDD8 (Neural precursor cell expressed developmentally downregulated protein 8) is an
ubiquitin-like protein that is covalently attached to a lysine residue of a protein substrate …

Numerous epidemiological, clinical, and animal studies showed that cardiac function and
manifestation of cardiovascular diseases (CVDs) are different between males and females …