Brain metabolism in Alzheimer's disease: biological mechanisms of exercise
L Xu, R Liu, Y Qin, T Wang - Translational neurodegeneration, 2023 - Springer
Alzheimer's disease (AD) is a major subtype of neurodegenerative dementia caused by long-
term interactions and accumulation of multiple adverse factors, accompanied by …
term interactions and accumulation of multiple adverse factors, accompanied by …
Linking the amyloid, tau, and mitochondrial hypotheses of Alzheimer's disease and identifying promising drug targets
Z Fišar - Biomolecules, 2022 - mdpi.com
Damage or loss of brain cells and impaired neurochemistry, neurogenesis, and synaptic and
nonsynaptic plasticity of the brain lead to dementia in neurodegenerative diseases, such as …
nonsynaptic plasticity of the brain lead to dementia in neurodegenerative diseases, such as …
Pathophysiological aspects and therapeutic armamentarium of Alzheimer's disease: recent trends and future development
BP Dave, YB Shah, KG Maheshwari… - Cellular and Molecular …, 2023 - Springer
Alzheimer's disease (AD) is the primary cause of dementia and is characterized by the death
of brain cells due to the accumulation of insoluble amyloid plaques, hyperphosphorylation of …
of brain cells due to the accumulation of insoluble amyloid plaques, hyperphosphorylation of …
Neuronal ApoE4 in Alzheimer's disease and potential therapeutic targets
L Zhang, Y Xia, Y Gui - Frontiers in aging neuroscience, 2023 - frontiersin.org
The most prevalent genetic risk factor for Alzheimer's disease (AD) is Apolipoprotein E
(ApoE), a gene located on chromosome 19 that encodes three alleles (e2, e3, and e4) that …
(ApoE), a gene located on chromosome 19 that encodes three alleles (e2, e3, and e4) that …
Molecular mechanisms in Alzheimer's disease and related potential treatments such as structural target convergence of antibodies and simple organic molecules
N Oumata, K Lu, Y Teng, C Cavé, Y Peng… - European Journal of …, 2022 - Elsevier
The amyloid cascade is the most frequently accepted hypothesis of Alzheimer's Disease
(AD). According to this hypothesis, the formation of plaques precedes the appearance of …
(AD). According to this hypothesis, the formation of plaques precedes the appearance of …
Effects of DHA on cognitive dysfunction in aging and Alzheimer's disease: The mediating roles of ApoE
X Zhang, T Yuan, X Chen, X Liu, J Hu, Z Liu - Progress in Lipid Research, 2023 - Elsevier
The prevalence of Alzheimer's disease (AD) continues to rise due to the increasing aging
population. Among the various genetic factors associated with AD, apolipoprotein E (ApoE) …
population. Among the various genetic factors associated with AD, apolipoprotein E (ApoE) …
Myelin repair in Alzheimer's disease: a review of biological pathways and potential therapeutics
This literature review investigates the significant overlap between myelin-repair signaling
pathways and pathways known to contribute to hallmark pathologies of Alzheimer's disease …
pathways and pathways known to contribute to hallmark pathologies of Alzheimer's disease …
Clinical and biological relevance of glial fibrillary acidic protein in Alzheimer's disease
Z Yang, K Sreenivasan, EN Toledano Strom… - Alzheimer's Research & …, 2023 - Springer
Introduction There is a tremendous need for identifying reliable blood-based biomarkers for
Alzheimer's disease (AD) that are tied to the biological ATN (amyloid, tau and …
Alzheimer's disease (AD) that are tied to the biological ATN (amyloid, tau and …
The role of bioenergetics in neurodegeneration
TA Strope, CJ Birky, HM Wilkins - International Journal of Molecular …, 2022 - mdpi.com
Bioenergetic and mitochondrial dysfunction are common hallmarks of neurodegenerative
diseases. Decades of research describe how genetic and environmental factors initiate …
diseases. Decades of research describe how genetic and environmental factors initiate …
The role of N-methyl-D-aspartate glutamate receptors in Alzheimer's disease: From pathophysiology to therapeutic approaches
W Liu, Y Li, T Zhao, M Gong, X Wang, Y Zhang… - Progress in …, 2023 - Elsevier
N-Methyl-D-aspartate glutamate receptors (NMDARs) are involved in multiple
physiopathological processes, including synaptic plasticity, neuronal network activities …
physiopathological processes, including synaptic plasticity, neuronal network activities …