Primary cilia project from the surface of most vertebrate cells and are key in sensing
extracellular signals and locally transducing this information into a cellular response. Recent …

Cells generate a highly diverse microtubule network to carry out different activities. This
network is comprised of distinct tubulin isotypes, tubulins with different post-translational …

Photoswitchable reagents are powerful tools for high-precision studies in cell biology. When
these reagents are globally administered yet locally photoactivated in two-dimensional (2D) …

Microtubules are cytoskeletal polymers that separate chromosomes during mitosis and
serve as rails for intracellular transport and organelle positioning. Manipulation of …

Colorectal cancer (CRC) is a common malignancy of the gastrointestinal tract with high
morbidity and mortality. Our previous studies have demonstrated that indole-chalcone …

The centrosome, a non‐membranous organelle, constrains various soluble molecules
locally to execute its functions. As the centrosome is surrounded by various dense …

Abstract PAR3/INSC/LGN form an evolutionarily conserved complex required for asymmetric
cell division in the developing brain, but its post-developmental function and disease …

The cytoskeleton is essential for spatial and temporal organisation of a wide range of
cellular and tissue‐level processes, such as proliferation, signalling, cargo transport …

Animal development involves numerous molecular events, whose spatiotemporal properties
largely determine the biological outcomes. Conventional methods for studying gene function …

Abstract Human immunodeficiency virus-1 (HIV-1) encodes simply 15 proteins and thus
depends on multiple host cellular factors for virus reproduction. Spastin, a microtubule …