Mitochondria play a primary role in cellular energetic metabolism, homeostasis, and death.
They possess their own multicopy genome, which is maternally transmitted. Mitochondria …

Mitochondria play a key role in a number of physiological events during all stages of life,
including the very first stages following fertilization. It is, therefore, important to understand …

Genetically modified pigs have become valuable tools for generating advances in animal
agriculture and human medicine. Importantly, in vitro production and manipulation of …

The aim of the present study was to assess the effects of L-carnitine, an enhancer of lipid
metabolism and mitochondrial activity, during in vitro maturation (IVM) on nuclear maturation …

Women presenting fertility problems are often helped by Assisted Reproductive Techniques
(ART), such as in vitro fertilization (IVF) programs. However, in many cases the etiology of …

It has been found that the quality of oocytes from obese women has been compromised and
subsequent embryos displayed arrested development. The compromised quality may be …

BACKGROUND It has been proposed that preimplantation embryo viability during culture
and following embryo transfer is associated with a 'quiet'metabolism. Viable embryos may …

Reduced oocyte and embryo quality are recognised as major factors in the problem of
disappointing fertility in high producing dairy cows. This review aims to shed more light on …

We have examined the potential role of fatty acid oxidation (FAO) in AMP‐activated protein
kinase (AMPK)‐induced meiotic maturation. Etomoxir and malonyl CoA, two inhibitors of …

In vivo and in vitro studies demonstrate that mitochondria in the oocyte, are susceptible to
damage by suboptimal pre/pregnancy conditions, such as obesity. These suboptimal …