The consensus that assisted reproduction technologies (ART), like in vitro fertilization, to
induce oxidative stress (ie, the known) belies how oocyte/zygote mitochondria—a major …

The objective was to determine whether adding L-carnitine in IVM/IVC medium enhanced
maturation and developmental competence of porcine oocytes in vitro. Oocyte maturation …

Successful embryo and fetal development is dependent on the quality of the oocyte from
which it was derived. Several studies to date have demonstrated the link between …

Although current embryo culture media are based on carbohydrate metabolism of embryos,
little is known about metabolism of endogenous lipids. L-carnitine is a β-oxidation cofactor …

In vitro-cultured oocytes are separated from the follicular micro-environment in vivo and are
more vulnerable than in vivo oocytes to changes in the external environment. This …

Bisphenol A (BPA) is synthetic organic compound that exhibits estrogen-like properties and
it induces mitochondrial superoxide production. Melatonin (Mela) protects against BPA …

Embryonic diapause (ED) is a temporary arrest of embryo development and is characterized
by delayed implantation in the uterus. ED occurs in blastocysts of less than 2% of …

Human assisted reproductive technology procedures are routinely performed in clinics
globally, and some of these approaches are now common in other mammals such as cattle …

Mito-TEMPO is a well-known mitochondria-specific superoxide scavenger. However, the
effect of Mito-TEMPO on porcine embryo development, to our knowledge, has not been …

Growing oocytes in vitro from the most immature stages until they are developmentally
competent is a major goal of reproductive technology, requiring fundamental knowledge of …