Postoperative systemic inflammatory dysregulation and corticosteroids: a narrative review
In some patients, the inflammatory‐immune response to surgical injury progresses to a
harmful, dysregulated state. We posit that postoperative systemic inflammatory dysregulation …
harmful, dysregulated state. We posit that postoperative systemic inflammatory dysregulation …
Dexamethasone and surgical-site infection
Background The glucocorticoid dexamethasone prevents nausea and vomiting after
surgery, but there is concern that it may increase the risk of surgical-site infection. Methods …
surgery, but there is concern that it may increase the risk of surgical-site infection. Methods …
Effect of dexamethasone on complications or all cause mortality after major non-cardiac surgery: multicentre, double blind, randomised controlled trial
K Asehnoune, C Le Moal, G Lebuffe, M Le Penndu… - bmj, 2021 - bmj.com
Objective To assess the effect of dexamethasone on complications or all cause mortality
after major non-cardiac surgery. Design Phase III, randomised, double blind, placebo …
after major non-cardiac surgery. Design Phase III, randomised, double blind, placebo …
[HTML][HTML] The safety of perioperative dexamethasone with antiemetic dosage in surgical patients with diabetes mellitus: a systematic review and meta-analysis
QY Pang, JY Wang, XL Liang, Y Jiang, HL Liu - Perioperative Medicine, 2023 - Springer
Background Dexamethasone is commonly used for antiemesis in surgical patients. It has
been confirmed that long-term steroid use increases blood glucose level in both diabetic …
been confirmed that long-term steroid use increases blood glucose level in both diabetic …
Perioperative dexamethasone administration does not increase the incidence of postoperative infection in total hip and knee arthroplasty: a retrospective analysis
AB Richardson, A Bala, SS Wellman, DE Attarian… - The Journal of …, 2016 - Elsevier
Background Dexamethasone is frequently used for the treatment of postoperative nausea
and vomiting and as an adjunct in multimodal postoperative analgesia after total joint …
and vomiting and as an adjunct in multimodal postoperative analgesia after total joint …
Perioperative ADministration of Dexamethasone And blood Glucose concentrations in patients undergoing elective non-cardiac surgery–the randomised controlled …
TB Corcoran, E O'Loughlin, MTV Chan… - European Journal of …, 2021 - journals.lww.com
Perioperative ADministration of Dexamethasone And blood Gluc... : European Journal of
Anaesthesiology | EJA Perioperative ADministration of Dexamethasone And blood Glucose …
Anaesthesiology | EJA Perioperative ADministration of Dexamethasone And blood Glucose …
[HTML][HTML] Dexamethasone and clinically significant postoperative nausea and vomiting: a prespecified substudy of the randomised perioperative administration of …
TB Corcoran, C Martin, E O'Loughlin, KM Ho… - British Journal of …, 2022 - Elsevier
Background Clinically significant postoperative nausea and vomiting (PONV) is a patient-
reported outcome which reflects patient experience. Although dexamethasone prevents …
reported outcome which reflects patient experience. Although dexamethasone prevents …
Intraoperative dexamethasone does not increase the risk of postoperative wound infection: a propensity score-matched post hoc analysis of the ENIGMA-II trial …
T Corcoran, J Kasza, TG Short… - BJA: British Journal …, 2017 - academic.oup.com
Background. In a post hoc analysis of the ENIGMA-II trial, we sought to determine whether
intraoperative dexamethasone was associated with adverse safety outcomes. Methods …
intraoperative dexamethasone was associated with adverse safety outcomes. Methods …
Antiemetic doses of dexamethasone and their effects on immune cell populations and plasma mediators of inflammation resolution in healthy volunteers
A Barden, M Phillips, LM Hill, EM Fletcher… - … and essential fatty acids, 2018 - Elsevier
Introduction The synthetic glucocorticoid dexamethasone is a commonly administered
antiemetic. It has immunosuppressive effects and may alter postoperative blood glucose …
antiemetic. It has immunosuppressive effects and may alter postoperative blood glucose …
A survey of anaesthetists' use of tranexamic acid in noncardiac surgery
Major bleeding in noncardiac surgery is common and associated with serious complications.
The antifibrinolytic agent tranexamic acid (TXA) reduces bleeding and may reduce the risk of …
The antifibrinolytic agent tranexamic acid (TXA) reduces bleeding and may reduce the risk of …